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Active, Not Recruiting
Diagnostic Utility of Otosight Middle Ear Scope
The purpose of this study is to compare the successful exam completion rate, the detection of middle ear fluid (versus no fluid), and the categorization of middle ear fluid (purulent …
Baylor Role: Lead Sponsor
Enrolling By Invitation
Lemborexant Augmentation of Naltrexone for Alcohol Craving and Sleep
Alcohol is one of the most popular substances used worldwide for thousands of years. Globally, harmful alcohol use continues to be a major public health and economic burden. The World …
Baylor Role: Lead Sponsor
Recruiting
Arginine Metabolism in Pediatric Type 2 Diabetes
In parallel with the childhood obesity epidemic, type 2 diabetes (T2D) in children is becoming a significant public health concern. The incidence of pediatric T2D increased by 50% during the …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Integration of HPV Vaccination and HPV-based Cervical Screening Into ARV Clinics: the H2VICTORY Trial
An effectiveness-implementation hybrid study is proposed to evaluate the effectiveness of a dual intervention of HPV vaccination and HPV-triage-and-treat to reduce the risk of cervical cancer and to study its …
Withdrawn
Mesenchymal Stem Cells for Age-Related Frailty
Frailty is an aging-related syndrome of impaired physiologic reserve and function across multiple organs, leading to increased vulnerability for adverse health outcomes. Frailty is associated with an increased risk for …
Baylor Role: Collaborator
Recruiting
Safety Evaluation of Fecal Microbiota Transplantation in Severe Alcoholic Hepatitis
Background: Alcoholic hepatitis (AH) is a major public health problem in the United States, caused by chronic alcohol consumption of more than 40-60 g/day. Approximately 5 million Americans are diagnosed …
Recruiting
Outcomes of Pulmonary Valve Replacement With the INSPIRIS (Model 11500A) Valve
The primary objective of our study is to contribute to the scarce body of literature on the mid-term durability and hemodynamics of the INSPIRIS Resilia (model 11500) bioprosthesis when implanted …
Baylor Role: Lead Sponsor
Recruiting
Implementation of Whole Genome Sequencing as Screening in a Diverse Cohort of Healthy Infants
The objective of this research protocol is to assess the impacts of genomic sequencing in healthy infants from ethnically and racially diverse communities as part of routine pediatric care. Investigators …
Baylor Role: Collaborator
Withdrawn
Pimavanserin for Insomnia in Veterans With Posttraumatic Stress Disorder: Proof of Concept
More treatments are needed to target insomnia in Veterans with Posttraumatic Stress Disorder. There is evidence to suggest that pimavanserin, a medication approved by the Food and Drug Administration for …
Baylor Role: Lead Sponsor
Enrolling By Invitation
Pilot Study of Brief Intervention to Support Diabetes Health-Related Quality of Life
The aims of this pilot study are to evaluate the feasibility, acceptability, preliminary impact, and costs of a brief behavioral intervention to support diabetes health-related quality of life, delivered remotely …
Baylor Role: Lead Sponsor