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Mesenchymal Stem Cells for Age-Related Frailty (External Link)
Frailty is an aging-related syndrome of impaired physiologic reserve and function across multiple organs, leading to increased vulnerability for adverse health outcomes. Frailty is associated with an increased risk for …
Baylor Role: Collaborator
Recruiting
Safety Evaluation of Fecal Microbiota Transplantation in Severe Alcoholic Hepatitis (External Link)
Background: Alcoholic hepatitis (AH) is a major public health problem in the United States, caused by chronic alcohol consumption of more than 40-60 g/day. Approximately 5 million Americans are diagnosed …
Recruiting
Outcomes of Pulmonary Valve Replacement With the INSPIRIS (Model 11500A) Valve (External Link)
The primary objective of our study is to contribute to the scarce body of literature on the mid-term durability and hemodynamics of the INSPIRIS Resilia (model 11500) bioprosthesis when implanted …
Baylor Role: Lead Sponsor
Recruiting
Implementation of Whole Genome Sequencing as Screening in a Diverse Cohort of Healthy Infants (External Link)
The objective of this research protocol is to assess the impacts of genomic sequencing in healthy infants from ethnically and racially diverse communities as part of routine pediatric care. Investigators …
Baylor Role: Collaborator
Withdrawn
Pimavanserin for Insomnia in Veterans With Posttraumatic Stress Disorder: Proof of Concept (External Link)
More treatments are needed to target insomnia in Veterans with Posttraumatic Stress Disorder. There is evidence to suggest that pimavanserin, a medication approved by the Food and Drug Administration for …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Pilot Study of Brief Intervention to Support Diabetes Health-Related Quality of Life (External Link)
The aims of this pilot study are to evaluate the feasibility, acceptability, preliminary impact, and costs of a brief behavioral intervention to support diabetes health-related quality of life, delivered remotely …
Baylor Role: Lead Sponsor
Recruiting
HR-EGG in Medically Refractory Gastroparesis (External Link)
Gastroparesis is a chronic digestive disorder defined by the symptoms of nausea, vomiting, bloating, and abdominal pain in the setting of objectively delayed gastric emptying without mechanical gastric outlet obstruction. …
Baylor Role: Collaborator
Recruiting
CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD (External Link)
Pediatric obsessive-compulsive disorder (OCD) is a common, chronic, and severe psychiatric disorder. Currently, many youth with OCD are treated with medication, such as a serotonin reuptake inhibitor (SRI); however, only …
Baylor Role: Lead Sponsor
Recruiting
Early Detection of Endotheliopathy Post-Transplant (External Link)
Primary Objectives: - To evaluate the proportion of pediatric patients undergoing Hematopoietic cell transplantation (HCT) who develop critical illness (defined by admission to the pediatric intensive care unit at St. …
Baylor Role: Collaborator
Recruiting
Intervention to Prevent Behavioral Health Symptoms Among Pandemic Affected Children (External Link)
The COVID-19 pandemic is having a profound impact on children globally, jeopardizing their sense of safety, security, and behavioral health. In addition to COVID-19, millions of children are still recovering …
Baylor Role: Collaborator