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Not Yet Recruiting
Microbiome Alterations With Xylitol (MAX) in Pregnancy (External Link)
After consenting to the study, pregnant participants who have a singleton gestation and are <20 weeks' gestation will be randomised into either the intervention arm ( 6.36grams of daily xylitol; …
Baylor Role:
Lead Sponsor
Recruiting
Clear Aligners for the Treatment of Dental Malocclusion in OI (External Link)
Osteogenesis imperfecta (OI) is a heritable connective tissue disorder leading to frequent fractures and bone deformities. In about 90% of individuals with OI, the disease is caused by dominant mutations …
Baylor Role:
Lead Sponsor
Recruiting
BiZact Tonsillectomy in the Pediatric Population (External Link)
Tonsillectomy is the second most common pediatric surgical procedure, with more than 280,000 performed in children under the age of 15 in the United States in 2010. The most common …
Baylor Role:
Lead Sponsor
Recruiting
Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors (External Link)
Treatment with CAdVEC: On the first day of your treatment, participants will receive an injection of CAdVEC into your tumor. A blood sample will be obtained from the participant before …
Baylor Role:
Lead Sponsor
Not Yet Recruiting
Dexmedetomidine vs Placebo for Pediatric Cleft Palate Repair (External Link)
The eligibility of the patient to participate in this study will be determined by the Investigator on the basis of the inclusion and exclusion criteria. Consent will be obtained from …
Baylor Role:
Lead Sponsor
Active, Not Recruiting
Dental Malocclusion and Craniofacial Development in OI (External Link)
Investigators will look at dental health in people with OI and will describe teeth misalignment and head and neck defects in individuals with moderate to severe Osteogenesis Imperfecta (OI). Investigators …
Baylor Role:
Lead Sponsor
Completed
Non Invasive Oral Cancer Screening Among HIV Infected Individuals (External Link)
If you agree to take part in this study, you will be asked to come to the clinic for 2 study visits. First Study Visit: - You will be asked …
Baylor Role:
Collaborator
Active, Not Recruiting
HPV-16/18 E6/E7-Specific T Lymphocytes, Relapsed HPV-Associated Cancers, HESTIA (External Link)
HPV is found in the cancer cells of more than half the patients with certain types of cancer, suggesting that it may play a role in causing the cancer. The …
Baylor Role:
Lead Sponsor
Completed
Saving Lives at Birth: Primary Prevention of Periodontal Disease in Relation to Preterm Birth in Malawi (External Link)
Significance and Impact: Adverse birth outcomes related to the length of gestation (preterm birth) are recognized as one of the most significant disorders in maternal-child health at a global scale. …
Baylor Role:
Lead Sponsor
Active, Not Recruiting
TGF-beta Resistant Cytotoxic T-lymphocytes in Treatment of EBV-positive Nasopharyngeal Carcinoma / RESIST-NPC (External Link)
Blood will be collected from the patient to make LMP/BARF1/EBNA1 (NPC)-specific T cells. To grow NPC-specific T cells we have to use special cells called antigen-presenting cells, which train the …
Baylor Role:
Lead Sponsor