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Recruiting
EBV Specific T-Lymphocytes for Treatment of EBV-Positive Lymphoma (External Link)
The patient will donate blood in order to make C7R-EBV T cells. Depending on how long ago the cells were generated, they have been frozen. To get the C7R to …
Baylor Role: Lead Sponsor
Recruiting
Fetal Repair of Complex Gastroschisis: A Safety and Feasibility Trial (External Link)
Gastroschisis is a congenital abdominal wall defect by which the intestinal structures eviscerate from the abdomen, with a current prevalence of 4.9 per 10,000 pregnancies in the United States. Not …
Baylor Role: Lead Sponsor
Recruiting
Arginine Metabolism in Pediatric Type 2 Diabetes (External Link)
In parallel with the childhood obesity epidemic, type 2 diabetes (T2D) in children is becoming a significant public health concern. The incidence of pediatric T2D increased by 50% during the …
Baylor Role: Lead Sponsor
Recruiting
Early Detection of Endotheliopathy Post-Transplant (External Link)
Primary Objectives: - To evaluate the proportion of pediatric patients undergoing Hematopoietic cell transplantation (HCT) who develop critical illness (defined by admission to the pediatric intensive care unit at St. …
Baylor Role: Collaborator
Recruiting
Intervention to Prevent Behavioral Health Symptoms Among Pandemic Affected Children (External Link)
The COVID-19 pandemic is having a profound impact on children globally, jeopardizing their sense of safety, security, and behavioral health. In addition to COVID-19, millions of children are still recovering …
Baylor Role: Collaborator
Recruiting
Safety and Efficacy of Devices Used in Fetoscopic Neural Tube Defect Repair Cases (External Link)
All patients who choose to undergo fetoscopic neural tube defect repair at Texas Children's Fetal Center will be offered participation in this research study by study investigators. Description of study …
Baylor Role: Collaborator
Recruiting
CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD (External Link)
Pediatric obsessive-compulsive disorder (OCD) is a common, chronic, and severe psychiatric disorder. Currently, many youth with OCD are treated with medication, such as a serotonin reuptake inhibitor (SRI); however, only …
Baylor Role: Lead Sponsor
Recruiting
Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission (External Link)
This is a pragmatic, open-label, multicenter randomized control trial (RCT) conducted in asymptomatic patients with IBD who have persistent moderate to severe endoscopic inflammation despite optimization of index TIM. This …
Baylor Role: Collaborator
Recruiting
Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection (External Link)
The hemolytic uremic syndrome (HUS) is the most serious complication of high-risk Shiga toxin-producing Escherichia coli (STEC) infection and the most common cause of acquired acute kidney injury in otherwise …
Baylor Role: Collaborator
Recruiting
Comparison of Recombinant Influenza Vaccine Versus Standard Egg-Based Inactivated Influenza Vaccine in Adults 18-64 Years (External Link)
This randomized, active comparator trial will compare the clinical efficacy of recombinant influenza vaccine (RIV) to standard-dose egg-based inactivated influenza vaccine (SD IIV) among adults aged 18-64 years. The primary …
Baylor Role: Collaborator