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Not Yet Recruiting
A Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain Management (External Link)
The management of pelvic floor overactivity (PFOA) using focal BoNT injection has been gaining clinical interest. Evidence has shown that BoNT injections to the levator ani in patients with CPP …
Baylor Role: Collaborator
Not Yet Recruiting
Implementation of Whole Genome Sequencing as Screening in a Diverse Cohort of Healthy Infants (External Link)
The objective of this research protocol is to assess the impacts of genomic sequencing in healthy infants from ethnically and racially diverse communities as part of routine pediatric care. Investigators …
Baylor Role: Collaborator
Not Yet Recruiting
IV Iron Trial for Anemia Related to Uterine Bleeding in Female Patients Presenting to the Emergency Department (External Link)
Iron deficiency anemia (IDA) is the most common hematologic disorder in the United States and worldwide. Patients with moderate to severe anemia often present to the acute care setting for …
Baylor Role: Lead Sponsor
Not Yet Recruiting
OCD Biomarker Survey Employing sEEG and Stimulation: The OBSESS Trial (External Link)
Obsessive-compulsive disorder (OCD) has a lifetime prevalence of 2-3% and is a major cause of global disability. Deep brain stimulation (DBS) is an effective treatment for patients with severe, treatment-resistant …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Lemborexant Augmentation of Naltrexone for Alcohol Craving and Sleep (External Link)
Alcohol is one of the most popular substances used worldwide for thousands of years. Globally, harmful alcohol use continues to be a major public health and economic burden. The World …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Arginine Metabolism in Pediatric Type 2 Diabetes (External Link)
In parallel with the childhood obesity epidemic, type 2 diabetes (T2D) in children is becoming a significant public health concern. The incidence of pediatric T2D increased by 50% during the …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Cortical rTMS as a Treatment for Depression (External Link)
The OFC is functionally connected to other cortical brain regions (e.g., prefrontal and parietal cortices) but also to subcortical areas in the dorsal striatum, a core reward circuitry region. The …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Post-operative Pain Management in Children With Supracondylar Humerus Fractures (External Link)
Prior to surgery, participants will be randomly assigned to a group that will determine whether they are prescribed an opioid vs non-opioid pain management plan at discharge. Each participants' parent …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Dexmedetomidine vs Placebo for Pediatric Cleft Palate Repair (External Link)
The eligibility of the patient to participate in this study will be determined by the Investigator on the basis of the inclusion and exclusion criteria. Consent will be obtained from …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Pediatric Dose Optimization for Seizures in Emergency Medical Services (External Link)
The Pediatric Dose Optimization for Seizures in Emergency Medical Services (PediDOSE) study is designed to improve how paramedics treat seizures in children on ambulances. Seizures are one of the most …
Baylor Role: Lead Sponsor