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Not Yet Recruiting
Closing -TB GAPs - for People Living With HIV: TB Guidance for Adaptable Patient-Centered Service (External Link)
Tuberculosis (TB) is the world's leading infectious cause of mortality and responsible for 1/3 of deaths in people living with human immunodeficiency virus (PLHIV). Children and adolescents living with HIV …
Baylor Role: Lead Sponsor
Recruiting
Diagnostic Utility of Otosight Middle Ear Scope (External Link)
The purpose of this study is to compare the successful exam completion rate, the detection of middle ear fluid (versus no fluid), and the categorization of middle ear fluid (purulent …
Baylor Role: Lead Sponsor
Withdrawn
Azacytidine During Anti-tuberculosis Therapy (External Link)
All study participants will have drug-sensitive TB and successfully complete 2 months of standard intensive phase 4-drug RHZE (rifampin, isoniazid, pyrazinamide, ethambutol). By definition, to have uncomplicated TB, participants will …
Recruiting
Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection (External Link)
The hemolytic uremic syndrome (HUS) is the most serious complication of high-risk Shiga toxin-producing Escherichia coli (STEC) infection and the most common cause of acquired acute kidney injury in otherwise …
Baylor Role: Collaborator
Not Yet Recruiting
Efficacy of ActiveMatrix on Spinal SSI Rate (External Link)
Postoperative spinal surgical site infections (SSI) have a significant effect on patient morbidity and mortality.1 Spinal SSI as well as other complications including pseudoarthrosis occur at a higher rate in …
Baylor Role: Lead Sponsor
Recruiting
Evaluating a New Stool Based qPCR for Diagnosis of Tuberculosis in Children and People Living With HIV (External Link)
Tuberculosis (TB) continues to be a leading cause of morbidity and mortality among children and people living with HIV (PLHIV). Despite significant progress in TB diagnostics, improvement of childhood TB …
Baylor Role: Collaborator
Recruiting
Micro-hematology Analyzer for Viral/Bacterial Description (External Link)
The purpose of the study is to evaluate the reliability and accuracy of a newly developed point-of-care analyzer, the CytoTracker, to measure complete blood count (CBC) parameters. The CytoTracker results …
Baylor Role: Collaborator
Not Yet Recruiting
DTG/3TC Fixed Dose Formulations for the Maintenance of Virological Suppression in Children With HIV Infection Aged 2 to <15 Years Old (External Link)
This study will include 370 children and young people aged 2 to less than 15 years old who are living with HIV and are being treated with anti-HIV medicines for …
Baylor Role: Collaborator
Recruiting
TETRAVI Multivirus CTL for Treatment of EBV, CMV, Adenovirus, and BK Infections Post Allogeneic SCT. (External Link)
The virus-specific T cells (VSTs) given to the patient will be thawed and injected into their intravenous line. To prevent an allergic reaction if the patient had a prior reaction …
Baylor Role: Lead Sponsor
Recruiting
Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis (External Link)
Approximately 5,000 children die from septic shock each year in the United States (US); thousands more die worldwide. Most children admitted with sepsis receive initial resuscitation in an emergency department …
Baylor Role: Collaborator