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Locating Biomarkers in OCD Through Behavioral Tasks
This is a research study in which BCM is collaborating with Brown University/Butler Hospital and University of Pittsburgh. BCM and Butler Hospital will be enrolling sites. Brown University and University …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA)
As many as 50% of autistic youth have at least 1 anxiety disorder. Cognitive-behavioral therapy (CBT) for autistic youth is effective at treating anxiety, but access is limited. We have …
Baylor Role: Lead Sponsor
Not Yet Recruiting
OCD Biomarker Survey Employing sEEG and Stimulation: The OBSESS Trial
Obsessive-compulsive disorder (OCD) has a lifetime prevalence of 2-3% and is a major cause of global disability. Deep brain stimulation (DBS) is an effective treatment for patients with severe, treatment-resistant …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Remote Game-based Exercise Program for Cognitive and Motor Function Improvement
This study aims to develop and validate a remote exercise intervention for individuals at risk of or experiencing dementia using a wearable sensor-enabled platform, called Tele-Exergame. This approach could preserve …
Baylor Role: Lead Sponsor
Recruiting
Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder
Cognitive-behavioral therapy (CBT) is an effective treatment for anxiety, yet access to CBT is limited for most families due to the cost, practicalities of attending in-person treatment sessions, and limited …
Baylor Role: Lead Sponsor
Recruiting
Enhancing Psychotherapy for Veterans and Service Members With PTSD and Anxiety
Anxiety disorders and posttraumatic stress disorder (PTSD) are among the leading mental health problems in the nation and are highly prevalent among service members and Veterans. The process of recovery …
Baylor Role: Lead Sponsor
Enrolling By Invitation
Cortical rTMS as a Treatment for Depression
The OFC is functionally connected to other cortical brain regions (e.g., prefrontal and parietal cortices) but also to subcortical areas in the dorsal striatum, a core reward circuitry region. The …
Baylor Role: Lead Sponsor
Recruiting
Transdiagnostic Behavioral Therapy for Anxiety and Depression in Autistic Adolescents
About 1 in 54 adolescents are estimated to be on the autism spectrum, with over half suffering from anxiety or depressive disorders. These disorders contribute to suicidality, family stress, social …
Baylor Role: Lead Sponsor
Enrolling By Invitation
Lemborexant Augmentation of Naltrexone for Alcohol Craving and Sleep
Alcohol is one of the most popular substances used worldwide for thousands of years. Globally, harmful alcohol use continues to be a major public health and economic burden. The World …
Baylor Role: Lead Sponsor
Withdrawn
Pimavanserin for Insomnia in Veterans With Posttraumatic Stress Disorder: Proof of Concept
More treatments are needed to target insomnia in Veterans with Posttraumatic Stress Disorder. There is evidence to suggest that pimavanserin, a medication approved by the Food and Drug Administration for …
Baylor Role: Lead Sponsor