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14 Results
Not Yet Recruiting
Locating Biomarkers in OCD Through Behavioral Tasks
This is a research study in which BCM is collaborating with Brown University/Butler Hospital and University of Pittsburgh. BCM and Butler Hospital will be enrolling sites. Brown University and University …
Baylor Role: Lead Sponsor
Recruiting
Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder
Cognitive-behavioral therapy (CBT) is an effective treatment for anxiety, yet access to CBT is limited for most families due to the cost, practicalities of attending in-person treatment sessions, and limited …
Baylor Role: Lead Sponsor
Recruiting
CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD
Pediatric obsessive-compulsive disorder (OCD) is a common, chronic, and severe psychiatric disorder. Currently, many youth with OCD are treated with medication, such as a serotonin reuptake inhibitor (SRI); however, only …
Baylor Role: Lead Sponsor
Recruiting
Imaging-Guided Low Intensity Focused Ultrasound (LIFU)
The current project will investigate a novel neurostimulation approach, low intensity focused ultrasound (LIFU), which combines non-invasiveness and a sharp spatial focus in deep brain regions. This open-label early feasibility …
Baylor Role: Lead Sponsor
Completed
Parent-based Treatment for Youth With Anxiety and Obsessive-compulsive Disorder
Anxiety and obsessive-compulsive disorders are the most common mental health disorders in childhood and adolescence. Parental accommodation of their children's avoidance, escape, safety behaviors are a set of parenting behaviors …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Phase II Adaptive Deep Brain Stimulation for Obsessive-Compulsive Disorder
ENROLLMENT: A subject is considered enrolled upon signing informed consent and deemed eligible to be screened by the investigator. The informed consent process may include discussions with the patients family …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Brain Recordings in Patients Undergoing Deep Brain Stimulation (DBS) for Severe Obsessive-Compulsive Disorder (OCD)
Obsessive-compulsive disorder effects approximately 2-3% of the population. The only established first-line treatments for OCD are cognitive-behavioral therapy (CBT) with exposure/response prevention and serotonin reuptake inhibitor medications (SRIs). Approximately 30-40% …
Baylor Role: Lead Sponsor
Withdrawn
Individual Versus Group Exposure With Response Prevention (ERP) for the Treatment of Obsessive Compulsive Disorder (OCD)
The purpose of the following study is to observe the effectiveness of group Exposure and Response Prevention verses individual Exposure and Response Prevention on patients with OCD for the use …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Development of Adaptive Deep Brain Stimulation for OCD
ENROLLMENT: A subject is considered enrolled upon signing informed consent, deemed eligible to be screened by the investigator. The informed consent process may include discussions with the patient¿s family and …
Baylor Role: Lead Sponsor
Completed
Parent-Led Cognitive-Behavioral Teletherapy for Anxiety in Youth With ASD
Anxiety disorders affect 50-80% of children with autism spectrum disorder (ASD) and are associated with significant life impairment and worsening trajectory without treatment. The most effective psychotherapy for anxiety in …
Baylor Role: Lead Sponsor