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Recruiting
PROmotion of COVID-19 BOOSTer VA(X)Ccination in the Emergency Department - PROBOOSTVAXED
I. Overview On January 22, 2020, Acting Health and Human Services Secretary Norris Cochran declared COVID-19 a national public health emergency, an action that eventually enabled emergency authorization for free …
Baylor Role: Collaborator
Not Yet Recruiting
High vs.Standard Dose Influenza Vaccine in Pediatric SOT Recipients
Study design: This is a phase II, multi-center, double-blind, randomized controlled immunogenicity and safety trial comparing two doses of HD-QIV or two doses of SD-QIV in pediatric SOT recipients. Hypotheses: …
Baylor Role: Collaborator
Not Yet Recruiting
Integration of HPV Vaccination and HPV-based Cervical Screening Into ARV Clinics: the H2VICTORY Trial
An effectiveness-implementation hybrid study is proposed to evaluate the effectiveness of a dual intervention of HPV vaccination and HPV-triage-and-treat to reduce the risk of cervical cancer and to study its …
Active, Not Recruiting
Multiple Myeloma Trial of Orally Administered Salmonella Based Survivin Vaccine
The vaccine will be administered orally (by mouth) as a solution mixed with sodium bicarbonate. Approximately 10 minutes prior to receiving the vaccine, participants will take sodium bicarbonate pills to …
Baylor Role: Lead Sponsor
Recruiting
Th-1 Dendritic Cell Immunotherapy Plus Standard Chemotherapy for Pancreatic Adenocarcinoma
The primary objective of this phase 1, first in man trial is to determine the safety, toxicity, and feasibility of delivering autologous dendritic cells (DCs) loaded with pancreatic adenocarcinoma lysate …
Baylor Role: Lead Sponsor
Active, Not Recruiting
BCG Vaccine for Health Care Workers as Defense Against COVID 19
Study design: A placebo-controlled adaptive multi-center randomized controlled trial. Study population: High risk HCW with direct patient contacts, defined as physician assistants, respiratory therapists, nurses, physicians or other HCWs working …
Baylor Role: Collaborator
Active, Not Recruiting
Sm-TSP-2 Schistosomiasis Vaccine in Healthy Ugandan Adults
The study will recruit up to 290 healthy adult males and non-pregnant females into a two-part clinical trial of a vaccine to protect against schistosomiasis caused by infection with S. …
Baylor Role: Lead Sponsor
Completed
Entolimod, an Adjuvant for Vaccine Augmentation
This is a single-blind (participants are blinded), pilot study with no therapeutic or diagnostic intent and limited drug exposure. The study will be conducted at Baylor College of Medicine in …
Baylor Role: Lead Sponsor
Completed
Study of Co-administered Na-APR-1 (M74) and Na-GST-1 in Gabonese Children
Double blind, randomized, controlled, dose-escalation Phase 1 clinical trial in hookworm-exposed children aged 6 to 10 years living in the area of Lambaréné, Gabon. Children will receive three doses of …
Baylor Role: Lead Sponsor
Completed
Multi-component Interventions to Increase HPV Vaccination in a Network of Pediatric Clinics
The purpose of the study is to determine the comparative effectiveness of a provider-only intervention and a parent plus provider intervention to increase initiation of HPV vaccination among male and …
Baylor Role: Collaborator