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Search Clinical Trials
Recruiting
Safe Babies: Parenting Action Plan ( PAP ) (External Link)
The purpose of this project is to evaluate whether prevention education using motivational interviewing focused on promoting positive maternal mental health, coping with inconsolable crying, life stress reduction, and positive …
Baylor Role:
Lead Sponsor
Recruiting
Pediatric Dose Optimization for Seizures in Emergency Medical Services (External Link)
The Pediatric Dose Optimization for Seizures in Emergency Medical Services (PediDOSE) study is designed to improve how paramedics treat seizures in children on ambulances. Seizures are one of the most …
Baylor Role:
Collaborator
Recruiting
Rett Syndrome Registry (External Link)
The Rett Syndrome Registry is a longitudinal observational study of individuals with MECP2 mutations and a diagnosis of Rett syndrome. Designed together with the IRSF Rett Syndrome Center of Excellence …
Baylor Role:
Collaborator
Recruiting
Cardiopulmonary Outcomes in Osteogenesis Imperfecta: BBD7708 (External Link)
This study is cross-sectional. At the participant's one study visit, data will be obtained at a single point in time and reflect the patients' current condition. Evaluations will include family …
Baylor Role:
Lead Sponsor
Recruiting
Clear Aligners for the Treatment of Dental Malocclusion in OI (External Link)
Osteogenesis imperfecta (OI) is a heritable connective tissue disorder leading to frequent fractures and bone deformities. In about 90% of individuals with OI, the disease is caused by dominant mutations …
Baylor Role:
Lead Sponsor
Recruiting
Imaging-Guided Low Intensity Focused Ultrasound (LIFU) (External Link)
The current project will investigate a novel neurostimulation approach, low intensity focused ultrasound (LIFU), which combines non-invasiveness and a sharp spatial focus in deep brain regions. This open-label early feasibility …
Baylor Role:
Lead Sponsor
Recruiting
HER2-specific Chimeric Antigen Receptor (CAR) T Cells for Children With Ependymoma (External Link)
PBTC-059 is a multicenter, Phase I and Surgical study of the treatment HER2-specific CAR T cells for patients with refractory or recurrent ependymoma. Phase I The primary objectives of the …
Baylor Role:
Collaborator
Active, Not Recruiting
Tolerability of Lopinavir Versus Dolutegravir for Children and Adolescents Living With HIV (External Link)
Dolutegravir, an antiretroviral drug to treat HIV, has recently been rolled out on a large scale across much of Africa. With paediatric formulations becoming increasingly available, dolutegravir is set to …
Completed
Orthofeet: A Prospective Proof of Concept Trial to Evaluate an Innovative Pain Relief Footwear (External Link)
A clinical study at the Baylor College of Medicine, to evaluate short and intermediate benefits and effectiveness of a novel pain relief footwear, called Orthofeet. This is a randomized crossed …
Not Yet Recruiting
Efficacy of ActiveMatrix on Spinal SSI Rate (External Link)
Postoperative spinal surgical site infections (SSI) have a significant effect on patient morbidity and mortality.1 Spinal SSI as well as other complications including pseudoarthrosis occur at a higher rate in …
Baylor Role:
Lead Sponsor