Search Clinical Trials

132 Results

Completed
High Dose Chemo/Radiotherapy and Hematopoietic Stem Cell Transplant for Patients With Multiple Sclerosis (External Link)
To participate in this study, patients will need to have a central line (a thin plastic catheter or tube that is placed during surgery into one of the large veins …
Baylor Role: Lead Sponsor
Withdrawn
Post Discharge Circadian Rhythms Post Adenotonsillectomy (External Link)
Wearable technology has tremendous advantages over current methods of assessing RTB activity in the post-discharge pediatric population after AT, which rely on quality of life (QOL) scales, caregiver and patient …
Baylor Role: Lead Sponsor
Completed
Nitric Oxide Supplementation in Argininosuccinic Aciduria (External Link)
The investigators will perform a double blind, randomized, placebo-controlled, crossover study of NO supplementation in ASA patients assessing endothelial function and blood pressure as primary endpoints, and markers of nitric …
Baylor Role: Lead Sponsor
Terminated
Efficacy of Micro-Patterned Foley Catheter to Reduce Catheter-Associated Urinary Tract Infection (External Link)
Roughly half of the two million nosocomial infections that occur each year are associated with the use of a medical device. Approximately 30 million urinary catheters are inserted each year …
Baylor Role: Lead Sponsor
Completed
One-Day Intervention for Depression and Impairment in Migraine Patients (External Link)
Adults with comorbid depression and migraine will be randomized to a 1-day (6-hour) workshop of Acceptance and Commitment Training + Migraine Education (ACT-ME) or Migraine Education only (MEO). The intervention …
Baylor Role: Lead Sponsor
Completed
Nitric Oxide Production in MELAS Syndrome (External Link)
What does the study involve? Individuals with MELAS syndrome will be admitted twice to the General Clinical Research Center (GCRC) at Texas Children's Hospital. Each time they will stay for …
Baylor Role: Lead Sponsor
Completed
Amitiza in Constipation Associated With PD (Parkinson's Disease) (External Link)
Parkinson's disease (PD) affects about one million people in the United States. It is a common neurological condition that is clinically defined by rigidity (muscle stiffness), bradykinesia (slowness of movement) …
Baylor Role: Lead Sponsor
Completed
Phase 1 Intrathecal Topotecan for Neoplastic Meningitis (External Link)
This is a multi-center, non-randomized pharmacokinetically-guided optimal dosing study of intraventricular topotecan in children with neoplastic meningitis. Topotecan will be administered daily for five consecutive days utilizing the schema shown …
Baylor Role: Lead Sponsor
Completed
A Randomized, Placebo-controlled, Tourette Syndrome Study. (External Link)
This study consists of three phases: Screening/Washout Phase, Double-Blind Phase and Taper Phase. SCREENING/WASHOUT PHASE: Your study doctor or his staff will review with you any medications that you are …
Baylor Role: Lead Sponsor
Terminated
Intrathecal Gemcitabine to Treat Neoplastic Meningitis, IT Gemcitabine (External Link)
WHAT IS INVOLVED IN THE STUDY? Before participating in this study, there will be a screening process. Administration: Gemcitabine will be received directly into the cerebrospinal fluid (fluid that circulates …
Baylor Role: Lead Sponsor