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Active, Not Recruiting
HER2-specific Chimeric Antigen Receptor (CAR) T Cells for Children With Ependymoma
PBTC-059 is a multicenter, Phase I and Surgical study of the treatment HER2-specific CAR T cells for patients with refractory or recurrent ependymoma. Phase I The primary objectives of the …
Baylor Role: Collaborator
Active, Not Recruiting
Remote Game-based Exercise Program for Cognitive and Motor Function Improvement
This study aims to develop and validate a remote exercise intervention for individuals at risk of or experiencing dementia using a wearable sensor-enabled platform, called Tele-Exergame. This approach could preserve …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Post IVIG Medication in Children With Immune Thrombocytopenia
Immune thrombocytopenia (ITP) is the most common acquired immune cytopenia in childhood, affecting 4-6 in 100,000 children. The pathophysiology of ITP is highly complex and incompletely understood. Accepted mechanisms include …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Multiple Myeloma Trial of Orally Administered Salmonella Based Survivin Vaccine
The vaccine will be administered orally (by mouth) as a solution mixed with sodium bicarbonate. Approximately 10 minutes prior to receiving the vaccine, participants will take sodium bicarbonate pills to …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Parent-based Treatment for Youth With Anxiety and Obsessive-compulsive Disorder
Anxiety and obsessive-compulsive disorders are the most common mental health disorders in childhood and adolescence. Parental accommodation of their children's avoidance, escape, safety behaviors are a set of parenting behaviors …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Phase II Adaptive Deep Brain Stimulation for Obsessive-Compulsive Disorder
ENROLLMENT: A subject is considered enrolled upon signing informed consent and deemed eligible to be screened by the investigator. The informed consent process may include discussions with the patients family …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Examining Validity and Sensitivity of Pressure-Mediated Reflection Spectroscopy
A diet rich in fruits and vegetables (F&Vs) is associated with lower risk of nutrition-related chronic diseases and all-cause mortality. Despite these benefits, the US population under-consumes F&Vs, with particularly …
Baylor Role: Collaborator
Active, Not Recruiting
Food Insecurity Screening and Intervention: From Hospital to Home
Screening / Enrollment: At enrollment the research coordinator will create daily epic report list, maintain notes on eligible subjects obtain informed consent, verify eligibility, have caregiver complete demographics questionnaire in …
Baylor Role: Lead Sponsor
Active, Not Recruiting
A Pilot Randomized Controlled Trial for Feasibility of Administering an AR Game to Postoperative Pediatric Cancer Patients
This is a pilot study to evaluate the feasibility of SpellBound's AR (augmented reality)-enabled scavenger hunt use among 20 pediatric cancer patients undergoing surgery.
Baylor Role: Collaborator
Active, Not Recruiting
Cyclosporine For The Treatment Of COVID-19(+)
1. OBJECTIVES 1.1 Primary Objectives 1.1.1 To assess the effect of a 7-day course of oral cyclosporine Neoral on clinical outcome using the World Health Organization (WHO) COVID Ordinal Clinical …