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VIRTUALLY SUPERVISED TELE-EXERCISE PLATFORM FOR ACCELERATING PLANTAR WOUND HEALING (External Link)
Foot ulceration is the most common and costly late complication of diabetes, with morbidity and mortality being worse than many cancers. It is estimated that up to one-third of people …
Baylor Role:
Lead Sponsor
Not Yet Recruiting
Heart Coherence Training on Vascular Ehlers-Danlos Syndrome Patients (External Link)
Vascular Ehlers Danlos Syndrome (VEDS) is caused by pathogenic variants of the COL3A1 gene, resulting abnormal Type III collagen protein. This impacts the body's connective tissue and makes people with …
Baylor Role:
Lead Sponsor
Recruiting
Hydrogen's Feasibility and Safety as a Therapy in ECPR (External Link)
The purpose of this project is to test the feasibility and safety of inhaled hydrogen gas (H2) administration as a rescue therapy during cardiac arrest requiring extracorporeal cardiopulmonary resuscitation (ECPR, …
Baylor Role:
Collaborator
Recruiting
Left vs Left Randomized Clinical Trial (External Link)
In this prospective, randomized, multi-center clinical trial, the investigators aim to prospectively evaluate the comparative effectiveness His or Left bundle branch pacing (His/LBBP) vs. biventricular pacing (BiVP) in patients with …
Baylor Role:
Lead Sponsor
Recruiting
Marfan Syndrome Moderate Exercise Trial II (External Link)
Marfan syndrome (MFS) is a distinctive connective tissue disorder with clinical phenotypes that affect multiple organ systems including the heart, bones, ligaments, and eyes, and are associated with significant risk …
Baylor Role:
Lead Sponsor
Completed
Game-Based Foot & Ankle Exercise for Those With Lower Extremity Edema (External Link)
Lower extremity edema (LE) is an accumulation of interstitial fluid volume in the legs and feet and commonly occurs in patients with diabetes, hypertension, kidney disease, heart failure, cirrhosis, cancer, …
Baylor Role:
Lead Sponsor
Completed
Evaluation of VITLS Compared to Traditional Inpatient Monitoring in Cardiac Shunt-Dependent Children (External Link)
Children with congenital heart disease who are cardiac shunt dependent are at increased risk for physiologic decompensation compared to non-shunt dependent children. This can lead to prolonged hospitalizations to facilitate …
Baylor Role:
Lead Sponsor
Recruiting
Oxytocin for Hypermobile Ehlers-Danlos Syndrome (External Link)
This will be a single-site study to evaluate the effect of IV oxytocin on chronic pain in female adult patients with hypermobile EDS. Oxytocin secretion in the body is dynamic …
Baylor Role:
Lead Sponsor
Recruiting
Platelet Function in Patients With Ischemic Stroke Treated With Anti-thrombotic or Thrombolytic (External Link)
In the past we used 30% lower dose of abciximab compared to the cardiac trials and the discontinued ABESTT stroke trial. There were no symptomatic intracranial hemorrhages or thromboyctopenia in …
Baylor Role:
Lead Sponsor
Recruiting
Smart Boot Use to Measure Offloading Adherence (External Link)
The purpose of this study is to help people with diabetes who develop neuropathic diabetic foot ulcers (DFUs). These ulcers, or sores, if left untreated can increase the chance of …
Baylor Role:
Collaborator