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Completed
Pramipexole as a Treatment for Cocaine Dependence (External Link)
In this protocol we propose to assess the impact of treatment with higher doses of the potent D2/3 agonist pramipexole, using the extended release preparation that has been shown to …
Baylor Role: Lead Sponsor
Terminated
Comparing Nasal Suction Devices in Children With Bronchiolitis: A Pilot Study (External Link)
Bronchiolitis is a viral illness and a common cause for admission to the hospital. Most patients with bronchiolitis are managed at home. The indications of hospitalization are poor feeding (due …
Baylor Role: Lead Sponsor
Completed
A Trial Comparing Single Intra-op Dose of Methadone Versus Placebo in Patients Undergoing Spine Surgery (External Link)
Scoliosis is a disease that involves lateral and/or rotational deformity of the spine and can affect up to 4% of the population. Typically, surgery is considered when Cobb's angle, which …
Baylor Role: Lead Sponsor
Completed
Peanut Oral Immunotherapy in Children With Peanut Allergy (External Link)
This is a phase I, open label study for the initial 12 month desensitization phase of peanut oral immunotherapy and a 2 year maintenance phase. Subjects will be recruited to …
Baylor Role: Lead Sponsor
Terminated
The Effects of Cyclosporin A in a Low Humidity Environment, on the Ocular Surface (External Link)
This is a pilot study designed to evaluate the effect of two conventional dry eye therapies, artificial tears to hydrate and cyclosporine A as an anti-inflammatory, on the irritation symptoms …
Baylor Role: Lead Sponsor
Terminated
Efficacy of Micro-Patterned Foley Catheter to Reduce Catheter-Associated Urinary Tract Infection (External Link)
Roughly half of the two million nosocomial infections that occur each year are associated with the use of a medical device. Approximately 30 million urinary catheters are inserted each year …
Baylor Role: Lead Sponsor
Completed
Exercise as a Behavioral Treatment for Cocaine Dependence (External Link)
This proposal represents an important research effort with considerable public health significance in that it will provide detailed behavioral and physiological data for a non-pharmacological intervention to treat stimulant addiction. …
Baylor Role: Lead Sponsor
Withdrawn
Androxal in Male Infertility (External Link)
It has been estimated that 4 to 5 million men in the United States are testosterone deficient, but fewer than 10% currently receive testosterone replacement therapy. There are many reasons …
Baylor Role: Lead Sponsor
Completed
Safety and Immunogenicity Study of Na-GST-1 With or Without CpG (External Link)
This is a Phase 1 randomized double-blind dose-escalation clinical trial in healthy hookworm-naïve adults conducted at the George Washington Medical Faculty Associates, Washington, DC, and the George Washington University School …
Baylor Role: Lead Sponsor
Completed
One-Day Intervention for Depression and Impairment in Migraine Patients (External Link)
Adults with comorbid depression and migraine will be randomized to a 1-day (6-hour) workshop of Acceptance and Commitment Training + Migraine Education (ACT-ME) or Migraine Education only (MEO). The intervention …
Baylor Role: Lead Sponsor