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EMPoWER Study - Strengths-based Behavioral Intervention for Youth With Type 1 Diabetes (External Link)
In preparation for the randomized clinical trial of a new behavioral intervention for preteens with type 1 diabetes and their parents, the study is first enrolling adolescents with type 1 …
Baylor Role: Lead Sponsor
Recruiting
Fetal Repair of Complex Gastroschisis: A Safety and Feasibility Trial (External Link)
Gastroschisis is a congenital abdominal wall defect by which the intestinal structures eviscerate from the abdomen, with a current prevalence of 4.9 per 10,000 pregnancies in the United States. Not …
Baylor Role: Lead Sponsor
Recruiting
Healthy Communities Through CHW Initiatives (External Link)
Social determinants of health (SODH) are environmental variables that determine quality-of-life outcomes and risks that are delineated into five domains. Inequities in SODH are directly associated with diabetes. Latino(a)s suffer …
Baylor Role: Collaborator
Recruiting
Trivalent CAR-T Cell in Acute B-Lineage Leukemia (TRICAR-ALL) (External Link)
The TRICAR-ALL T-cells were made in the laboratory by stimulating the patient's blood with growth factors to make the T cells grow. To get the CD19/CD20/CD22 antibody and 4-1BB to …
Baylor Role: Lead Sponsor
Recruiting
Closing -TB GAPs - for People Living With HIV: TB Guidance for Adaptable Patient-Centered Service (External Link)
Tuberculosis (TB) is the world's leading infectious cause of mortality and responsible for 1/3 of deaths in people living with human immunodeficiency virus (PLHIV). Children and adolescents living with HIV …
Baylor Role: Lead Sponsor
Recruiting
EVD Drainage Data and Intracranial Pressure (ICP) Measurements (External Link)
Hydrocephalus is caused by excess cerebrospinal fluid in the brain that can lead to lethargy, seizures, and comas. There is no cure for it nor is there any way to …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors (External Link)
Approximately 15-24 subjects will participate in the treatment part of this study. Maximum of 180 mL of blood (not exceeding 3ml/kg/day) is collected from patients to grow the T cells …
Baylor Role: Lead Sponsor
Recruiting
Baylor Infant and Toddler Biomarker of Nutrition Study (External Link)
Early life nutrition is recognized as key determinant of short- and long-term health. However, a lack of objective, reliable, and valid methods to determine what exactly children makes it difficult …
Baylor Role: Lead Sponsor
Recruiting
Addressing Caregiver Wellbeing and Improving Child Development (External Link)
The study aim is to implement a bundle of neurodevelopmental interventions and employ an intergenerational care model, focused on the needs of young children and their parents to maximize health …
Baylor Role: Lead Sponsor
Enrolling By Invitation
Cortical rTMS as a Treatment for Depression (External Link)
The OFC is functionally connected to other cortical brain regions (e.g., prefrontal and parietal cortices) but also to subcortical areas in the dorsal striatum, a core reward circuitry region. The …
Baylor Role: Lead Sponsor