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Clinical Evaluation of Montelukast in Veterans With Gulf War Illness (External Link)
Background: Approximately 30% of Gulf War Veterans (1990-1991) suffer from Gulf War Illness (GWI), a chronic condition characterized by disabling symptoms in multiple domains. Animal models and human data suggest …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan (External Link)
There is a crisis in the treatment of the imminently suicidal patient. Acute Suicidal Depression (ASD) is a life-threatening illness which requires rapid relief. A number of behavioral programs with …
Baylor Role: Collaborator
Not Yet Recruiting
GpCRC Pediatric Gastroparesis Registry 2 (External Link)
An observational study to investigate the natural history and clinical course of children, adolescents, and young adults with symptoms of gastroparesis (e.g., nausea, vomiting, abdominal pain, bloating, distention) with either …
Baylor Role: Collaborator
Not Yet Recruiting
Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion (External Link)
This is a phase I/II study of haploidentical HCT (HHCT) with ex vivo TCRαβ+ and CD19+ depletion using the CliniMACS device in patients with hematological malignancies and non-malignant disorders. HHCT …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Left vs Left Randomized Clinical Trial (External Link)
In this prospective, randomized, multi-center clinical trial, the investigators aim to prospectively evaluate the comparative effectiveness His or Left bundle branch pacing (His/LBBP) vs. biventricular pacing (BiVP) in patients with …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Safety and Efficacy of Fetoscopes Used in Fetoscopic Selective Laser Photocoagulation (External Link)
All patients who choose to undergo fetoscopic selective laser photocoagulation (S-PLC) at Texas Children's Fetal Center will be offered participation in this research study by study investigators. Description of study …
Baylor Role: Collaborator
Not Yet Recruiting
Survivorship Care for Women Living With Ovarian Cancer: (POSTCARE-O) (External Link)
Study Design We will conduct a 2-arm randomized controlled trial to evaluate the impact of a telehealth delivered survivorship transition care process. Ovarian cancer survivors (120) will be randomly allocated …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Neoadjuvant Durvalumab and Tremelimumab With and Without Chemotherapy for Mesothelioma (External Link)
Study Design: The study will be a two-arm, randomized non-comparative Phase Ib/IIa study of induction dual immunotherapy with durvalumab/tremelimumab OR platinum chemotherapy (cisplatin or carboplatin) and pemetrexed chemotherapy plus dual …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Integrating Food Rx With Best Feeding Practices With EFNEP (External Link)
The purpose of the pilot study is to test the FFYF feeding curriculum material and procedures for implementation, staff training, recruitment, and data collection.
Baylor Role: Lead Sponsor
Recruiting
Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder (External Link)
Cognitive-behavioral therapy (CBT) is an effective treatment for anxiety, yet access to CBT is limited for most families due to the cost, practicalities of attending in-person treatment sessions, and limited …
Baylor Role: Lead Sponsor