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Pimavanserin for Insomnia in Veterans With Posttraumatic Stress Disorder: Proof of Concept
More treatments are needed to target insomnia in Veterans with Posttraumatic Stress Disorder. There is evidence to suggest that pimavanserin, a medication approved by the Food and Drug Administration for …
Baylor Role: Lead Sponsor
Enrolling By Invitation
Pilot Study of Brief Intervention to Support Diabetes Health-Related Quality of Life
The aims of this pilot study are to evaluate the feasibility, acceptability, preliminary impact, and costs of a brief behavioral intervention to support diabetes health-related quality of life, delivered remotely …
Baylor Role: Lead Sponsor
Recruiting
CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD
Pediatric obsessive-compulsive disorder (OCD) is a common, chronic, and severe psychiatric disorder. Currently, many youth with OCD are treated with medication, such as a serotonin reuptake inhibitor (SRI); however, only …
Baylor Role: Lead Sponsor
Recruiting
Early Detection of Endotheliopathy Post-Transplant
Primary Objectives: - To evaluate the proportion of pediatric patients undergoing Hematopoietic cell transplantation (HCT) who develop critical illness (defined by admission to the pediatric intensive care unit at St. …
Baylor Role: Collaborator
Recruiting
Intervention to Prevent Behavioral Health Symptoms Among Pandemic Affected Children
The COVID-19 pandemic is having a profound impact on children globally, jeopardizing their sense of safety, security, and behavioral health. In addition to COVID-19, millions of children are still recovering …
Baylor Role: Collaborator
Recruiting
Safety and Efficacy of Devices Used in Fetoscopic Neural Tube Defect Repair Cases
All patients who choose to undergo fetoscopic neural tube defect repair at Texas Children's Fetal Center will be offered participation in this research study by study investigators. Description of study …
Baylor Role: Collaborator
Recruiting
Game-Based Foot & Ankle Exercise for Those With Lower Extremity Edema
Lower extremity edema (LE) is an accumulation of interstitial fluid volume in the legs and feet and commonly occurs in patients with diabetes, hypertension, kidney disease, heart failure, cirrhosis, cancer, …
Baylor Role: Lead Sponsor
Recruiting
EBV Specific T-Lymphocytes for Treatment of EBV-Positive Lymphoma
The patient will donate blood in order to make C7R-EBV T cells. Depending on how long ago the cells were generated, they have been frozen. To get the C7R to …
Baylor Role: Lead Sponsor
Enrolling By Invitation
Evaluation of VITLS Compared to Traditional Inpatient Monitoring in Cardiac Shunt-Dependent Children
Children with congenital heart disease who are cardiac shunt dependent are at increased risk for physiologic decompensation compared to non-shunt dependent children. This can lead to prolonged hospitalizations to facilitate …
Baylor Role: Lead Sponsor
Recruiting
Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission
This is a pragmatic, open-label, multicenter randomized control trial (RCT) conducted in asymptomatic patients with IBD who have persistent moderate to severe endoscopic inflammation despite optimization of index TIM. This …
Baylor Role: Collaborator