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Recruiting
EASE: The Materna Prep Pivotal Study (External Link)
Primary effectiveness endpoint: Reduction in the rate of pelvic muscle injury defined as complete or partial detachment of the levator ani muscle diagnosed via ultrasound imaging at 3-month follow-up. Primary …
Completed
TechStep: Technology-based Stepped Care to Stem Transgender Adolescent Risk Transmission (External Link)
TechStep is a three-arm, technology-based randomized controlled trial (RCT), with a stepped care approach, among high-risk HIV-negative transgender feminine, transgender masculine, and gender non-conforming youth and young adults for reducing …
Baylor Role: Collaborator
Completed
Comparison of Men's Prevention Apps to Research Efficacy (External Link)
COMPARE is part of the iTech NIH U19, which has an overall goal to develop innovative technology-focused interventions addressing the HIV prevention and care continuum for youth. In years 1-2 …
Baylor Role: Collaborator
Active, Not Recruiting
Development of Adaptive Deep Brain Stimulation for OCD (External Link)
ENROLLMENT: A subject is considered enrolled upon signing informed consent, deemed eligible to be screened by the investigator. The informed consent process may include discussions with the patient¿s family and …
Baylor Role: Lead Sponsor
Recruiting
Clinical and Basic Investigations Into Congenital Disorders of Glycosylation (External Link)
The investigators are conducting a natural history study of patients with congenital disorders of glycosylation (CDG). The study will look into the progression of the disease amongst the participants and …
Baylor Role: Collaborator
Active, Not Recruiting
Sm-TSP-2 Schistosomiasis Vaccine in Healthy Ugandan Adults (External Link)
The study will recruit up to 290 healthy adult males and non-pregnant females into a two-part clinical trial of a vaccine to protect against schistosomiasis caused by infection with S. …
Baylor Role: Lead Sponsor
Enrolling By Invitation
Dynamic Neural Mechanisms of Audiovisual Speech Perception (External Link)
Understanding speech is one of the most important functions of the human brain. We use information from both the auditory modality (the voice the of person we are talking to) …
Baylor Role: Collaborator
Recruiting
Deep Brain Stimulation (DBS) for Depression Using Directional Current Steering and Individualized Network Targeting (External Link)
Treatment-resistant depression (TRD) is a major worldwide burden. Major depression has a lifetime prevalence of ~15% across developed countries. Up to a third of patients fail to respond adequately to …
Baylor Role: Lead Sponsor
Active, Not Recruiting
MTG201 Plus Nivolumab in Patients With Relapsed Pleural Mesothelioma (External Link)
This is a study of the efficacy and safety of MTG201 given by intratumoral injection to patients with malignant pleural mesothelioma who have failed front line chemotherapy. Patients will also …
Baylor Role: Collaborator
Recruiting
Fetal Endotracheal Occlusion (FETO) in the Resolution of Pulmonary Hypertension in Fetuses With Severe CDH (External Link)
Enrollment Women carrying a fetus with severe CDH and a normal karyotype will undergo routine clinical evaluation. The fetus will be 28+0/7 to 31+6/7 weeks of gestational age and have …
Baylor Role: Collaborator