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Search Clinical Trials
Completed
Vancomycin vs. Nitazoxanide to Treat Recurrent C. Difficile Colitis (External Link)
Clostridium difficile is the leading cause of nosocomial diarrheal disease associated with antibiotic therapy. This is a debilitating condition with substantial morbidity and a mortality that used to be said …
Baylor Role:
Collaborator
Completed
Vancomycin vs. Vancomycin Plus Gentamycin in Treatment of MRSA Infection (External Link)
Treatment of bacteremic infection (infection associated with positive blood cultures) due to Staphylococcus aureus has become increasingly problematic as a result of the increasing prevalence of strains that are resistant …
Baylor Role:
Collaborator
Terminated
Steroid Treatment for Sickle Cell Pain Crisis (External Link)
In the United States, 9% of African Americans have sickle cell trait and 1 in 600 has sickle cell disease. Vaso- occlusive crises in sickle cell disease remain a frequent …
Baylor Role:
Lead Sponsor
Completed
Hemangioma Associated With High Rates of Morbidity (External Link)
Large hemangiomas of the face can be associated with anomalies of the blood vessels of head and chest. The acronym PHACES indicates the association of Posterior fossa and other brain …
Baylor Role:
Collaborator
Completed
Fecal Bacterial Flora in Clostridium Difficile-Associated Diarrhea (External Link)
Clostridium difficile associated colitis is an increasing problem in hospitals throughout the developed world; the number of cases has increased, and the failure to respond to conventional therapy has become …
Baylor Role:
Collaborator
Completed
Phase 1 Intrathecal Topotecan for Neoplastic Meningitis (External Link)
This is a multi-center, non-randomized pharmacokinetically-guided optimal dosing study of intraventricular topotecan in children with neoplastic meningitis. Topotecan will be administered daily for five consecutive days utilizing the schema shown …
Baylor Role:
Lead Sponsor
Withdrawn
Lymphocytic B-Leukemia (B-CLL) w/Human IL-2 Gene Modified & Human CD40 Ligand-Expressing Autologous Tumor Cells (External Link)
This is a phase I trial to assess the safety of depleting regulatory T (Treg) cells using 1-3 doses of an interleukin-2 immunotoxin directed to the CD25 antigen (denileukin diftitox, …
Baylor Role:
Lead Sponsor
Completed
Dexmedetomidine in Pediatric Tonsillectomy (External Link)
Dexmedetomidine, an alpha 2 agonist provides some analgesia without respiratory depression. Children undergoing tonsillectomy and adenoidectomy occasionally have episodes of respiratory obstruction in the recovery room following administration of opioids. …
Baylor Role:
Lead Sponsor
Terminated
Bone Marrow Transplantation, Hemoglobinopathies, SCALLOP (External Link)
Prior to any bone marrow transplant, we will need patients to: - Answer questions about their medical history; - Undergo a physical examination; - Have tests done to see how …
Baylor Role:
Collaborator
Withdrawn
Pharmacogenomics in Pulmonary Arterial Hypertension (External Link)
This study will make use of a large population of well defined patients with Pulmonary Arterial Hypertension who were enrolled in Encysive Pharmaceutical's STRIDE clinical trials or who have received …
Baylor Role:
Collaborator