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Completed
Carvedilol for Psychostimulant Dependence (External Link)
This study examines whether carvedilol prolongs abstinence in recently abstinent cocaine dependent participants.
Baylor Role: Collaborator
Completed
Fetal Surgery for Moderate Left Sided Congenital Diaphragmatic Hernia. (External Link)
Isolated Congenital Diaphragmatic Hernia (CDH) can be diagnosed in the prenatal period, and remains associated with a 30 % chance of perinatal death and morbidity mainly because of pulmonary hypoplasia …
Baylor Role: Collaborator
Completed
Modafinil - Escitalopram Study for Cocaine Dependence (External Link)
In this application, we propose an augmentation strategy intended to improve the efficacy of modafinil as a potential treatment for cocaine dependence. Recent data indicates that during chronic treatment modafinil …
Baylor Role: Lead Sponsor
Completed
Multisite Controlled Trial of Cocaine Vaccine (External Link)
This 18-week, placebo-controlled randomized clinical trial among 300 cocaine dependent patients is designed to test the efficacy of a newly developed active vaccine against cocaine (TA-CD). TA-CD vaccine consists of …
Baylor Role: Lead Sponsor
Completed
Role of HIV on Glutathione Synthesis and Oxidative Stress (External Link)
HIV infection is associated the development of increased oxidative stress and deficiency of glutathione (GSH), the dominant endogenous antioxidant protein, but the underlying mechanisms contributing to GSH deficiency are hitherto …
Baylor Role: Lead Sponsor
Recruiting
Quality Improvement Project - Evaluation of Current Standard of Care for Feeding Practices in the NICU (External Link)
This is a quality improvement project to evaluate the current standard of care of nutritional management for very low birth weight infants receiving donor human milk products in the NICU …
Baylor Role: Lead Sponsor
Completed
Abdominal Symptom Phenotype Study in Children (External Link)
Functional gastrointestinal (GI) disorders (FGIDs), in particular irritable bowel syndrome (IBS) in adults and children, are among the most common and costly health care problems in the US. IBS disproportionately …
Baylor Role: Lead Sponsor
Withdrawn
Developing a Diabetic Foot Ulcer Protocol (External Link)
This pilot study will be conducted in Harris County Hospital District (HCHD) Community Health Centers and Wound Care Clinics. The study will use random assignment of patients who meet inclusion …
Baylor Role: Collaborator
Completed
Energy Expenditure and Physical Activity in Preschoolers (External Link)
In this study, the investigators will apply advanced technology (fast-response room calorimetry, doubly labeled water (DLW), accelerometers and miniaturized HR monitors) and sophisticated mathematical modeling techniques (cross-sectional time series, CSTS …
Baylor Role: Lead Sponsor
Completed
Intranasal Oxytocin and Maternal Neglect (External Link)
The investigators plan to conduct fMRI scanning with a group of mothers who are blindly and randomly assigned either intranasal oxytocin or a placebo. Aim 1: To determine whether intranasal …
Baylor Role: Lead Sponsor