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1052 Results
Completed
Seattle-PAP Bubble Nasal CPAP and Work of Breathing
The primary outcome variable is work of breathing (WOB) over a two hour period, estimated from pressure-rate products, which are assessed with 6 Fr (2 mm) catheters placed in the …
Baylor Role: Collaborator
Completed
The IMPULSE Study: Pilot
Continuous-flow (CF) left ventricular assist devices (LVADs) are an important tool in the treatment of end-stage heart failure, affording patients significantly improved quantity and quality of life. In recent years, …
Baylor Role: Lead Sponsor
Completed
The Tolerability of Saracatinib in Subjects With Lymphangioleiomyomatosis (LAM) (SLAM-1)
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder caused by mutations in tuberous sclerosis complex 1 (TSC1) or tuberous sclerosis complex 2 (TSC2) tumor suppressor genes. TSC is characterized …
Completed
Peanut Oral Immunotherapy in Children With Peanut Allergy (Peanut Flour)
This is a phase I, open label study for the initial 12 month desensitization phase of peanut oral immunotherapy and a 2 year maintenance phase. Subjects will be recruited to …
Baylor Role: Lead Sponsor
Completed
A Pilot Study To Evaluate The Preliminary Safety And Feasibility Of The Materna Medical Device
Over 80% of women who deliver vaginally will sustain a vaginal tear, and roughly half of all women will suffer from permanent pelvic muscle damage that may lead to pelvic …
Baylor Role: Lead Sponsor
Completed
Diabetes Strengths Study - Pilot of Provider-delivered Strengths-based Intervention
The purpose of this study is to pilot test a newly developed strengths-based clinical intervention delivered by diabetes care providers in the context of routine ambulatory diabetes care, designed to …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Fetoscopic Meningomyelocele Repair Study
Spina bifida can be a devastating neurological congenital anomaly . It results from incomplete closure of the neural tube between 22 and 28 embryological days. Its incidence is approximately 1-2 …
Baylor Role: Lead Sponsor
Terminated
Lenalidomide Maintenance Therapy in Stage IIIB/IV Non-small Cell Lung Cancer
For patients with stage IIIB/IV non-small cell lung cancer, who did not progress after first line chemotherapy, lenalidomide 10mg/day orally will be administered as maintenance therapy until disease progression or …
Baylor Role: Collaborator
Active, Not Recruiting
Microbiome And Multi'Omics In Preterm Birth: The Bacteria And Birth Study
Specific Aim 1. Longitudinal maternal (vaginal, oral, skin, gut), fetal (oral, skin, gut) and placental (basal plate and parenchyma) 16S-based metagenomic profiling with inferred metagenomics will reveal distinct microbial communities …
Baylor Role: Lead Sponsor
Completed
Multivirus-specific T Cells for the Treatment of Virus Infections After Stem Cell Transplant
These VST lines have been made at Baylor College of Medicine from donors for other transplant patients or other normal donors some of whom were from the National Marrow Donor …
Baylor Role: Collaborator