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Completed
MEDI4736 Or MEDI4736 + Tremelimumab In Surgically Resectable Malignant Pleural Mesothelioma (External Link)
Subjects with MPM will undergo surgical mediastinal lymph node biopsy (cervical mediastinoscopy) and simultaneous surgical biopsy of the pleural tumor by thoracoscopy, at which time tumor tissue (at least 2 …
Baylor Role: Lead Sponsor
Terminated
Non-Invasive Direct Current Stimulation for Cognition in Schizophrenia (External Link)
Cognitive functions and EEG correlates will be thoroughly assessed in schizophrenia patients undergoing a tDCS treatment and compared with patients receiving a placebo stimulation. The treatment will involve 20 minutes …
Baylor Role: Lead Sponsor
Completed
OHI--Randomized Control Trial to Evaluate Efficacy, Acceptability, and Perception of Benefit of an Innovative Custom AFO (External Link)
The investigators propose a randomized control trial to evaluate long term effects and effectiveness of Moore Balance Brace (MBB) ankle foot orthoses (AFO) in reducing risk of falling in older …
Recruiting
Using Game-based Exercise to Improve Balance in Cancer Patients (External Link)
Cancer patients with chemotherapy-induced peripheral neuropathy (CIPN) have deficits in sensory and motor skills leading to inappropriate proprioceptive feedback, impaired postural control and high fall risk. This study will investigate …
Baylor Role: Lead Sponsor
Completed
Fetal 3D Study (Fetal Body Composition and Volumes Study) (External Link)
The NICHD Fetal Growth Study was a multi-site, prospective cohort study designed to establish a standard for normal fetal growth (velocity) and size for gestational age in the U.S. population. …
Baylor Role: Collaborator
Completed
Effects of Diet Interventions on Monocytes in Metabolic Syndrome (External Link)
Subjects with hypertriglyceridemia and metabolic syndrome are being recruited and receive diet interventions with either a high-saturated fat diet or a low-fat high protein diet for 4 days (days 1-4) …
Baylor Role: Lead Sponsor
Completed
First STEPS- Study of Type 1 in Early Childhood and Parenting Support (External Link)
Research Design and Methods Overview of Study Design & Procedure. The aim of this randomized controlled trial (RCT) is to determine the efficacy of a stepped care intervention that provides …
Baylor Role: Collaborator
Completed
Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia (External Link)
Participants with Chiari Malformation type I and syringomyelia will be randomized to either have a posterior fossa decompression done with or without duraplasty. The participant will then return to the …
Baylor Role: Collaborator
Terminated
Safety and Efficacy of Saracatinib In Subjects With Lymphangioleiomyomatosis (External Link)
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder caused by mutations in tuberous sclerosis complex 1 (TSC1) or TSC2 tumor suppressor genes. TSC is characterized by tumors in a …
Baylor Role: Lead Sponsor
Active, Not Recruiting
T Cells Expressing HER2-specific Chimeric Antigen Receptors(CAR) for Patients With HER2-Positive CNS Tumors (External Link)
First, to find out if HER2 is expressed in the patient's brain cancer, the investigators will need to obtain the tissue block or tissue specimen that was used to make …
Baylor Role: Lead Sponsor