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Recruiting
Arginine Metabolism in Youth With Type 2 Diabetes
In parallel with the youth obesity epidemic, type 2 diabetes (T2D) in youth is becoming a significant public health concern. The incidence of pediatric T2D increased by 50% during the …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Integration of HPV Vaccination and HPV-based Cervical Screening Into ARV Clinics: the H2VICTORY Trial
An effectiveness-implementation hybrid study is proposed to evaluate the effectiveness of a dual intervention of HPV vaccination and HPV-triage-and-treat to reduce the risk of cervical cancer and to study its …
Withdrawn
Mesenchymal Stem Cells for Age-Related Frailty
Frailty is an aging-related syndrome of impaired physiologic reserve and function across multiple organs, leading to increased vulnerability for adverse health outcomes. Frailty is associated with an increased risk for …
Baylor Role: Collaborator
Recruiting
Safety Evaluation of Fecal Microbiota Transplantation in Severe Alcoholic Hepatitis
Background: Alcoholic hepatitis (AH) is a major public health problem in the United States, caused by chronic alcohol consumption of more than 40-60 g/day. Approximately 5 million Americans are diagnosed …
Recruiting
Implementation of Whole Genome Sequencing as Screening in a Diverse Cohort of Healthy Infants
The objective of this research protocol is to assess the impacts of genomic sequencing in healthy infants from ethnically and racially diverse communities as part of routine pediatric care. Investigators …
Baylor Role: Collaborator
Withdrawn
Pimavanserin for Insomnia in Veterans With Posttraumatic Stress Disorder: Proof of Concept
More treatments are needed to target insomnia in Veterans with Posttraumatic Stress Disorder. There is evidence to suggest that pimavanserin, a medication approved by the Food and Drug Administration for …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Pilot Study of Brief Intervention to Support Diabetes Health-Related Quality of Life
The aims of this pilot study are to evaluate the feasibility, acceptability, preliminary impact, and costs of a brief behavioral intervention to support diabetes health-related quality of life, delivered remotely …
Baylor Role: Lead Sponsor
Recruiting
HR-EGG in Medically Refractory Gastroparesis
Gastroparesis is a chronic digestive disorder defined by the symptoms of nausea, vomiting, bloating, and abdominal pain in the setting of objectively delayed gastric emptying without mechanical gastric outlet obstruction. …
Baylor Role: Collaborator
Recruiting
CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD
Pediatric obsessive-compulsive disorder (OCD) is a common, chronic, and severe psychiatric disorder. Currently, many youth with OCD are treated with medication, such as a serotonin reuptake inhibitor (SRI); however, only …
Baylor Role: Lead Sponsor
Recruiting
Safety and Efficacy of Devices Used in Fetoscopic Neural Tube Defect Repair Cases
All patients who choose to undergo fetoscopic neural tube defect repair at Texas Children's Fetal Center will be offered participation in this research study by study investigators. Description of study …
Baylor Role: Collaborator