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Terminated
Primary Versus Delayed Surgical Therapy for Pediatric Spontaneous Pneumothorax
1. All children presenting to Texas Children's Hospital with a primary spontaneous pneumothorax will be potentially eligible for the study. 2. After the diagnosis has been made and initial medical …
Baylor Role: Lead Sponsor
Completed
Micro-mobile Foot Compression and Diabetic Foot
Diabetic foot ulceration (DFU) is a common and largely preventable complication. While most of these ulcers can be treated successfully, some will persist and become infected. Ultimately, nearly one fifth …
Baylor Role: Lead Sponsor
Recruiting
Pediatric Acute Gastrointestinal Bleeding Registry
A. Specific Aims/Objectives: The goal of this study is to identify significant clinical and laboratory risk factors in pediatric patients with significant upper gastrointestinal bleeding. This is defined as bleeding …
Baylor Role: Collaborator
Recruiting
Bladder Directed vs. Pelvic Floor Therapy in IC/BPS
This will be a prospective randomized trial of pelvic floor therapy vs. bladder directed therapy. The study target population consists of females, aged 18 to 85 years of age with …
Baylor Role: Collaborator
Completed
Metabolomics for Biomarker Discovery in Children With EoE
Eosinophilic esophagitis (EoE) is a disorder of the esophagus triggered by food and/or environmental allergens and is characterized by symptoms of esophageal dysfunction and eosinophilia of the esophagus. The standard …
Baylor Role: Collaborator
Recruiting
Throat and Other HPV-Related Cancers in Men: Identifying Them Early
PRIMARY SCIENTIFIC OBJECTIVES: I. To determine the association of antibodies to human papillomavirus type 16 (HPV16) early (E) antigens and circulating HPV16 DNA (cHPVDNA) with oral HPV16 prevalence. II. To …
Baylor Role: Lead Sponsor
Recruiting
Assessment of Heparin Binding Protein for the Prediction of Severe Sepsis
The primary objective of this study is to use HBP concentration to indicate the presence, or outcome, of severe sepsis (including septic shock) at admission and to predict the outcome …
Baylor Role: Collaborator
Completed
Fetal Hemoglobin Induction Treatment Metformin
This is a dose escalation, pilot study for subjects with sickle cell anemia (SCA) disease to determine if metformin has a beneficial effect on the treatment and quality of life …
Baylor Role: Lead Sponsor
Completed
Clinical Trial of Wireless CranioFacial Nerve Stimulation (CFNS) for the Treatment of CranioFacial Neuropathic Pain
Subjects will be randomized at enrollment into either a delayed or immediate continuation group. The immediate continuation group will immediately continue with the stimulation after a 30-day trial period and …
Baylor Role: Collaborator
Completed
Phase I/II Study OF Metformin in Combination With Cisplatin and Radiation in Head and Neck Squamous Cell Carcinoma
Information from laboratory studies and retrospective studies of patients with this disease has shown that the addition of metformin (a commonly used medicine for treating diabetes) to chemotherapy and radiation …
Baylor Role: Lead Sponsor