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Completed
Game-Based Foot & Ankle Exercise for Those With Lower Extremity Edema (External Link)
Lower extremity edema (LE) is an accumulation of interstitial fluid volume in the legs and feet and commonly occurs in patients with diabetes, hypertension, kidney disease, heart failure, cirrhosis, cancer, …
Baylor Role:
Lead Sponsor
Completed
Evaluation of VITLS Compared to Traditional Inpatient Monitoring in Cardiac Shunt-Dependent Children (External Link)
Children with congenital heart disease who are cardiac shunt dependent are at increased risk for physiologic decompensation compared to non-shunt dependent children. This can lead to prolonged hospitalizations to facilitate …
Baylor Role:
Lead Sponsor
Completed
Hypotension in Children With Down Syndrome With Anesthesia Induction (External Link)
Children generally undergo induction of anesthesia by inhalation of sevoflurane. This is particularly relevant for children with developmental delays as to avoid placement of an IV while awake. However, children …
Baylor Role:
Lead Sponsor
Completed
Photo-Protection Trial (NB-UVB vs. Placebo) in High-risk Hospitalized COVID-19 Patients (External Link)
Study Design This is a multi-center, double blind, randomized control trial designed to assess the safety and efficacy of daily NB-UVB light for patients presenting to site hospitals over the …
Baylor Role:
Collaborator
Completed
Marfan Syndrome Moderate Exercise Pilot (External Link)
Marfan syndrome (MFS) affects multiple organ systems including the heart, bones, ligaments, and eyes, and is associated with significant risk of aortic dissection. Given anecdotal reports of aortic dissection, limited …
Baylor Role:
Lead Sponsor
Completed
Electrical Stimulation to Accelerate Wound Healing (External Link)
Electrical stimulation may offer a unique treatment option to heal complicated and recalcitrant wounds, improve flap and graft survival, and even reduce the likelihood of ulceration. Electrical stimulation has been …
Baylor Role:
Lead Sponsor
Completed
Comparative Effectiveness of Two Acellular Matrices (Dermacell vs. Integra) for Management of Deep Diabetic Foot Ulcers (External Link)
Diabetes-related foot ulcers (DFUs) are a leading cause of hospitalization and amputation worldwide, and account for 33% of all direct costs of diabetes care in the US. Ulcers requiring acute …
Baylor Role:
Lead Sponsor
Completed
Cardiac Biomarkers in Patients With Single Ventricle Physiology (External Link)
All neonates with congenital heart disease undergoing stage one palliation (Norwood procedure, Damus-Kaye-Stansel procedure) at Texas Children's Hospital will be regularly monitored for B-type natriuretic peptide (BNP) and Troponin level …
Baylor Role:
Lead Sponsor
Completed
Micro-mobile Foot Compression and Diabetic Foot (External Link)
Diabetic foot ulceration (DFU) is a common and largely preventable complication. While most of these ulcers can be treated successfully, some will persist and become infected. Ultimately, nearly one fifth …
Baylor Role:
Lead Sponsor
Completed
Exclusive Human Milk Feeding in Infants With Single Ventricle Physiology (External Link)
This is a single blinded (physician investigator), randomized, controlled trial to evaluate growth velocity and clinical outcomes in infants with single ventricle physiology fed an exclusive human milk diet during …
Baylor Role:
Collaborator