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Active, Not Recruiting
Transdiagnostic Behavioral Therapy for Anxiety and Depression in Autistic Adolescents
About 1 in 54 adolescents are estimated to be on the autism spectrum, with over half suffering from anxiety or depressive disorders. These disorders contribute to suicidality, family stress, social …
Baylor Role: Lead Sponsor
Active, Not Recruiting
A Practical Platform for In-Home Remote Monitoring of Cognitive Frailty
The investigators are proposing to evaluate the feasibility and accuracy of the Frailty Meter (FM), a cutting-edge video-based solution for remotely assessing frailty. FM determines frailty phenotypes, such as weakness, …
Baylor Role: Lead Sponsor
Active, Not Recruiting
An Innovative Platform for Objective Monitoring of Instrumental Activities of Daily Living
This innovative platform, called IADLSys, will detect the timing and type of IADL for a wide range of daily functions, and will also monitor the user's physical activity and life-space. …
Active, Not Recruiting
Phase II Adaptive Deep Brain Stimulation for Obsessive-Compulsive Disorder
ENROLLMENT: A subject is considered enrolled upon signing informed consent and deemed eligible to be screened by the investigator. The informed consent process may include discussions with the patients family …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Brain Recordings in Patients Undergoing Deep Brain Stimulation (DBS) for Severe Obsessive-Compulsive Disorder (OCD)
Obsessive-compulsive disorder effects approximately 2-3% of the population. The only established first-line treatments for OCD are cognitive-behavioral therapy (CBT) with exposure/response prevention and serotonin reuptake inhibitor medications (SRIs). Approximately 30-40% …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Development of Adaptive Deep Brain Stimulation for OCD
ENROLLMENT: A subject is considered enrolled upon signing informed consent, deemed eligible to be screened by the investigator. The informed consent process may include discussions with the patient¿s family and …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Development of Adaptive Deep Brain Stimulation for OCD (Phase 1a)
RECRUITMENT: Potential participants will be referred to our program by their treating clinicians, who will be made aware of our study through direct clinician-clinician letters and emails. Subjects may also …
Baylor Role: Lead Sponsor
Active, Not Recruiting
DBS of the Lateral Habenula in Treatment-Resistant Depression
This research study includes the following parts: 1. medical, psychiatric, and cognitive evaluations 2. implantation of the brain stimulation system, and 3. follow up including programming and psychiatric testing after …
Active, Not Recruiting
Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita
Dyskeratosis congenita (DC) is an inherited multisystem disorder, which classically presents with a clinical triad of skin pigment abnormalities, nail dystrophy, and oral leukoplakia. DC is part of a spectrum …
Baylor Role: Collaborator