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Multiple Myeloma Trial of Orally Administered Salmonella Based Survivin Vaccine (External Link)
The vaccine will be administered orally (by mouth) as a solution mixed with sodium bicarbonate. Approximately 10 minutes prior to receiving the vaccine, participants will take sodium bicarbonate pills to …
Baylor Role:
Lead Sponsor
Active, Not Recruiting
Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging (External Link)
Chronic aortic aneurysms are permanent and localized dilations of the aorta that remain asymptomatic for long periods of time, but continue to increase in diameter before they eventually rupture. Left …
Baylor Role:
Collaborator
Active, Not Recruiting
PRecIsion Medicine in CardiomyopathY (External Link)
This is a retrospective cohort study of pediatric hypertrophic cardiomyopathy (HCM) patients using chart and registry review methodology. The studies objective is to develop and validate a sudden cardiac death …
Baylor Role:
Collaborator
Active, Not Recruiting
Prospective Assessment of the Deep Vein Thrombosis (DVT) in Hospitalized Obstetrics Patients (External Link)
After initial admission of the patients for Cesarean Section, Vaginal Delivery or any other antepartum hospitalization, patients undergo extensive counseling regarding various aspects of the Duplex Ultrasonography procedure and the …
Baylor Role:
Lead Sponsor
Active, Not Recruiting
BEnefits of Stroke Treatment Delivered Using a Mobile Stroke Unit (External Link)
There are many ways that use of a MSU might prove valuable in stroke patients, but we will focus on acute ischemic stroke (AIS) and treatment with IV tissue plasminogen …
Baylor Role:
Collaborator
Active, Not Recruiting
Randomized Trial of Lenalidomide, Bortezomib, Dexamethasone vs High-Dose Treatment With SCT in MM Patients up to Age 65 (External Link)
The drugs, lenalidomide, bortezomib, and dexamethasone, are approved by the FDA. They have not been approved in the combination for multiple myeloma or any other type of cancer. Bortezomib is …
Baylor Role:
Collaborator
Active, Not Recruiting
Innovative Approaches to Gauge Progression of Sturge-Weber Syndrome (External Link)
This study is one of three projects of an NIH Rare Disease Clinical Research Consortium focused on brain blood vessel malformations in three different rare diseases. The focus of this …
Baylor Role:
Collaborator