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Completed
Electrical Stimulation for Critically Ill Post-Covid-19 Patients
20 subjects that were hospitalized due to severe COVID-19 infection and present neuromuscular complications (i.e., hospital acquired weakness due to neuromyopathy) will be recruited after the first phase of this …
Baylor Role: Lead Sponsor
Completed
Hypotension in Children With Down Syndrome With Anesthesia Induction
Children generally undergo induction of anesthesia by inhalation of sevoflurane. This is particularly relevant for children with developmental delays as to avoid placement of an IV while awake. However, children …
Baylor Role: Lead Sponsor
Completed
Electrical Stimulation for Critically Ill Covid-19 Patients
Phase I: The purpose of this study is to test feasibility and proof-of-concept effectiveness of lower extremity electrical stimulation (EE) therapy to prevent muscular complications of COVID-19 including hospital-acquired weakness …
Baylor Role: Lead Sponsor
Completed
Pimavanserin for Insomnia In Veterans With Posttraumatic Stress Disorder
More treatments are needed to target insomnia in Veterans with Posttraumatic Stress Disorder. There is evidence to suggest that pimavanserin, a medication approved by the Food and Drug Administration for …
Baylor Role: Lead Sponsor
Completed
Effect of Opioids on Ventilation in Children With Obstructive Sleep Apnea
Ventilatory suppression in children following opioid administration is of obvious concern, especially following routine surgical procedures (i.e. adenotonsillectomy). It is thought that patients with obstructive sleep apnea (OSA) have increased …
Baylor Role: Lead Sponsor
Completed
Electrical Stimulation to Accelerate Wound Healing
Electrical stimulation may offer a unique treatment option to heal complicated and recalcitrant wounds, improve flap and graft survival, and even reduce the likelihood of ulceration. Electrical stimulation has been …
Baylor Role: Lead Sponsor
Completed
Cytokine Persistence as a Marker of Inflammation in the at Risk, Low Socioeconomic Status Pediatric Population
Obstructive sleep apnea (OSA) is a common multisystem disorder, affecting up to 10% of the pediatric population. There is scant data about OSA and adenotonsillectomy (AT) outcomes in the very …
Baylor Role: Lead Sponsor
Completed
Pimavanserin Treatment in TS
Tourette Syndrome is typically treated with drugs that block or reduce the function of dopamine (a brain chemical involved in movement). However, many of these drugs have adverse effects including …
Completed
Promoting the Psychological Health of Women With SCI: A Virtual World Intervention
The purpose of this project is to test the efficacy of an internet-based psychological health enhancement program for women with spinal cord injury. The intervention will occur in Second Life …
Baylor Role: Collaborator
Completed
Chronic Liver Disease in Urea Cycle Disorders
Urea cycle disorders (UCDs) are among the most common inborn errors of liver metabolism.With early diagnosis and improved treatments, the survival of individuals with UCDs has improved, and this improved …
Baylor Role: Lead Sponsor