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133 Results

Active, Not Recruiting
Addressing Caregiver Wellbeing and Improving Child Development (External Link)
The study aim is to implement a bundle of neurodevelopmental interventions and employ an intergenerational care model, focused on the needs of young children and their parents to maximize health …
Baylor Role: Lead Sponsor
Enrolling By Invitation
Cortical rTMS as a Treatment for Depression (External Link)
The OFC is functionally connected to other cortical brain regions (e.g., prefrontal and parietal cortices) but also to subcortical areas in the dorsal striatum, a core reward circuitry region. The …
Baylor Role: Lead Sponsor
Active, Not Recruiting
A Single-Session Intervention for Adolescents and Young Adults With Internalizing Problems (External Link)
The mental health of adolescents and young adults (AYA) has greatly been impacted since the beginning of the pandemic. With the increasing number of AYA experiencing depression and anxiety, paired …
Baylor Role: Lead Sponsor
Recruiting
Transdiagnostic Behavioral Therapy for Anxiety and Depression in Autistic Adolescents (External Link)
About 1 in 54 adolescents are estimated to be on the autism spectrum, with over half suffering from anxiety or depressive disorders. These disorders contribute to suicidality, family stress, social …
Baylor Role: Lead Sponsor
Completed
Lemborexant Augmentation of Naltrexone for Alcohol Craving and Sleep (External Link)
Alcohol is one of the most popular substances used worldwide for thousands of years. Globally, harmful alcohol use continues to be a major public health and economic burden. The World …
Baylor Role: Lead Sponsor
Withdrawn
Pimavanserin for Insomnia in Veterans With Posttraumatic Stress Disorder: Proof of Concept (External Link)
More treatments are needed to target insomnia in Veterans with Posttraumatic Stress Disorder. There is evidence to suggest that pimavanserin, a medication approved by the Food and Drug Administration for …
Baylor Role: Lead Sponsor
Recruiting
CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD (External Link)
Pediatric obsessive-compulsive disorder (OCD) is a common, chronic, and severe psychiatric disorder. Currently, many youth with OCD are treated with medication, such as a serotonin reuptake inhibitor (SRI); however, only …
Baylor Role: Lead Sponsor
Completed
Transcranial Direct Current Stimulation (tDCS) (External Link)
Sample size (n=10) is convenient and designed to explore acceptability and feasibility. Participants who are enrolled will be provided a tDCS device to use for a period of four weeks. …
Baylor Role: Lead Sponsor
Recruiting
Rett Syndrome Registry (External Link)
The Rett Syndrome Registry is a longitudinal observational study of individuals with MECP2 mutations and a diagnosis of Rett syndrome. Designed together with the IRSF Rett Syndrome Center of Excellence …
Baylor Role: Collaborator
Recruiting
Imaging-Guided Low Intensity Focused Ultrasound (LIFU) (External Link)
The current project will investigate a novel neurostimulation approach, low intensity focused ultrasound (LIFU), which combines non-invasiveness and a sharp spatial focus in deep brain regions. This open-label early feasibility …
Baylor Role: Lead Sponsor