Search Clinical Trials

133 Results

Completed
Treatment Strategy to Prevent Mood Disorders Following Traumatic Brain Injury (External Link)
Traumatic brain injury (TBI) is a leading cause of death and disability among young adults. Mood disorders are the most frequent psychiatric complication of TBI, and have a large impact …
Baylor Role: Lead Sponsor
Completed
Namenda (Memantine) for Non-Motor Symptoms in Parkinson's Disease (External Link)
To evaluate the effects of Memantine on non-motor symptoms in patients with Parkinson's disease. Parkinson's disease (PD) affects about one million people in the United States. It is a common …
Baylor Role: Lead Sponsor
Completed
Tolerability and Efficacy of Switch From Oral Selegiline to Orally Disintegrating Selegiline (Zelapar) in Patients With Parkinson's Disease (External Link)
This is an open label, multicenter, 6 week study of the conversion from oral selegiline to orally disintegrating selegiline in PD patients with or without motor fluctuations, and currently taking …
Baylor Role: Lead Sponsor
Completed
Cognitive Behavior Therapy for Treating Anxiety in People With Dementia (External Link)
Dementia is an illness that causes memory problems; changes in behavior; and difficulty with thinking, making decisions, and carrying out daily activities. Many people with dementia also have anxiety, and …
Baylor Role: Lead Sponsor
Withdrawn
Quantitative and Qualitative Changes in Neural Efferent Receptors (External Link)
Twenty-five (25) spinal cord injury patients, as part of their annual cystoscopic screening for squamous cell carcinoma, will be included in this study. Approximately twenty-five (25) control patients without spinal …
Baylor Role: Lead Sponsor
Completed
Prevention of Urinary Tract Infection (UTI) in Persons With Spinal Cord Injury (SCI) (External Link)
This clinical trial will be take place in a total of 7 medical centers that care for Spinal cord injury (SCI) and Spina Bifida patients. A total of 160 patients …
Baylor Role: Lead Sponsor
Withdrawn
Temozolomide and Topotecan in Treating Patients With Primary CNS Lymphoma (External Link)
OBJECTIVES: Primary - Determine the complete radiologic response rate in patients with primary CNS lymphoma treated with salvage chemotherapy comprising temozolomide and topotecan. Secondary - Determine the median and failure-free …
Baylor Role: Collaborator
Completed
Study to Treat Major Depressive Disorder With a New Medication (External Link)
Depressive disorders are among the most disabling medical conditions worldwide and currently available treatments fall short of addressing this large public health burden. Dysfunction within the brain reward system is …
Baylor Role: Collaborator
Available
Compassionate Use of Tetrabenazine in the Treatment of Abnormal Movements (External Link)
The purpose of the protocol is to provide compassionate use of an efficacious drug, with few side effects, in an attempt to get rid of a variety of incapacitating dyskinesias …
Completed
Continuous Tremor Assessment During Daily Activities (External Link)
The specific aim of this study is to evaluate if tremor severity and quality of life can be improved more using continuous home monitoring along with traditional assessments versus traditional …
Baylor Role: Collaborator