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Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors (External Link)
Approximately 15-24 subjects will participate in the treatment part of this study. Maximum of 180 mL of blood (not exceeding 3ml/kg/day) is collected from patients to grow the T cells …
Baylor Role:
Lead Sponsor
Not Yet Recruiting
Marfan Syndrome and Loeys-Dietz Syndrome Moderate Exercise Trial II (External Link)
Marfan syndrome (MFS) and Loeys-Dietz syndrome (LDS) are distinct connective tissue disorders with overlapping clinical phenotypes that affect multiple organ systems including the heart, bones, ligaments, and eyes, and are …
Baylor Role:
Lead Sponsor
Not Yet Recruiting
Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion (External Link)
This is a phase I/II study of haploidentical HCT (HHCT) with ex vivo TCRαβ+ and CD19+ depletion using the CliniMACS device in patients with hematological malignancies and non-malignant disorders. HHCT …
Baylor Role:
Lead Sponsor
Not Yet Recruiting
Dexmedetomidine vs Placebo for Pediatric Cleft Palate Repair (External Link)
The eligibility of the patient to participate in this study will be determined by the Investigator on the basis of the inclusion and exclusion criteria. Consent will be obtained from …
Baylor Role:
Lead Sponsor