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Oxytocin for Hypermobile Ehlers-Danlos Syndrome (External Link)
This will be a single-site study to evaluate the effect of IV oxytocin on chronic pain in female adult patients with hypermobile EDS. Oxytocin secretion in the body is dynamic …
Baylor Role:
Lead Sponsor
Active, Not Recruiting
Patch vs. No Patch Fetoscopic Meningomyelocele Repair Study (External Link)
Spina bifida can be a devastating neurological congenital anomaly. It results from incomplete closure of the neural tube between 22 and 28 embryological days. Its incidence is approximately 1-2 per …
Baylor Role:
Lead Sponsor
Active, Not Recruiting
N-Acetylcysteine in Biliary Atresia After Kasai Portoenterostomy (External Link)
Biliary atresia (BA) is a disease characterized by fibro-obliteration of extrahepatic bile ducts leading to impaired bile flow (Sokol et al., 2007). BA is treated with the Kasai portoenterostomy (KP), …
Baylor Role:
Lead Sponsor
Active, Not Recruiting
Oral Care in Infants With Gastroschisis (External Link)
Breast milk is recommended for most infants by the American Academy of Pediatrics as there are multiple benefits. However, some infants, such as extremely premature infants, are unable to receive …
Baylor Role:
Lead Sponsor
Active, Not Recruiting
Dental Malocclusion and Craniofacial Development in OI (External Link)
Investigators will look at dental health in people with OI and will describe teeth misalignment and head and neck defects in individuals with moderate to severe Osteogenesis Imperfecta (OI). Investigators …
Baylor Role:
Lead Sponsor
Active, Not Recruiting
Exclusive Human Milk Feeding in Infants With Single Ventricle Physiology (External Link)
This is a single blinded (physician investigator), randomized, controlled trial to evaluate growth velocity and clinical outcomes in infants with single ventricle physiology fed an exclusive human milk diet during …
Baylor Role:
Collaborator
Active, Not Recruiting
Urinary Biomarkers of OI Pathobiology (External Link)
Osteogenesis Imperfecta (OI) is a rare disorder that causes bones to break easily. People with OI may have broken bones with little or no trauma, dentinogenesis imperfecta (DI), and, in …
Baylor Role:
Lead Sponsor
Active, Not Recruiting
Use of Human Milk Cream to Decrease Length of Stay in Extremely Premature Infants (External Link)
The primary hypothesis of the study is that infants who receive an exclusive HM-based diet with the addition of a HM-derived cream caloric (Cream group) will have a shorter length …
Baylor Role:
Lead Sponsor
Active, Not Recruiting
Genomic Sequencing for Childhood Risk and Newborn Illness (External Link)
The objective of this research protocol is to conduct a randomized clinical trial to assess the benefits and risks of adding the information from a genomic sequencing report to physician-mediated …
Baylor Role:
Collaborator
Active, Not Recruiting
Fetoscopic Meningomyelocele Repair Study (External Link)
Spina bifida can be a devastating neurological congenital anomaly . It results from incomplete closure of the neural tube between 22 and 28 embryological days. Its incidence is approximately 1-2 …
Baylor Role:
Lead Sponsor