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SCOPE-CLI: Shifting Care and Outcomes for Patients With Endangered Limbs (External Link)
An estimated 8 million individuals in America are affected by peripheral arterial disease (PAD). One of its extreme expressions is Critical Limb Ischemia (CLI). It is one of the most …
Baylor Role:
Collaborator
Completed
Electrical Stimulation to Accelerate Wound Healing (External Link)
Electrical stimulation may offer a unique treatment option to heal complicated and recalcitrant wounds, improve flap and graft survival, and even reduce the likelihood of ulceration. Electrical stimulation has been …
Baylor Role:
Lead Sponsor
Recruiting
EO2 Oxygen Delivery To Study Success Rate of Surgically Closed Wounds (External Link)
Surgical wound (e.g., post minor amputation, reconstruction surgery, or surgical incision) complications such as infection, dehiscence, necrotic tissue, surgical revision, and poor cosmesis are unfortunately highly prevalent in patients undergoing …
Baylor Role:
Lead Sponsor
Completed
OHI--Randomized Control Trial to Evaluate Efficacy, Acceptability, and Perception of Benefit of an Innovative Custom AFO (External Link)
The investigators propose a randomized control trial to evaluate long term effects and effectiveness of Moore Balance Brace (MBB) ankle foot orthoses (AFO) in reducing risk of falling in older …
Withdrawn
The Effect of Ticagrelor on 15-Epi-Lipoxin A4 and Inflammation (External Link)
Clopidogrel, ticagrelor and prasugrel are routinely used for platelet inhibition in addition to aspirin in patients after acute coronary syndromes. The platelet inhibition and patient outcomes (PLATO) trial showed that …
Baylor Role:
Lead Sponsor
Completed
Using a Tailored Health Information Technology Driven Intervention to Improve Health Literacy and Medication Adherence (External Link)
Physicians seeing patients in the outpatient clinics will write patient's statin and/or antiplatelet prescription and the patient's cell phone numbers on an Optical Mark Recognition (OMR) sheet. The sheet will …
Baylor Role:
Collaborator
Completed
Patients With Intermittent Claudication Injected With ALDH Bright Cells (External Link)
Peripheral Artery Disease (PAD) occurs when arteries in the arms and legs (most often the legs) become narrowed by plaque. Because of this plaque, patients with PAD are also at …
Unknown Status
Effect of Short Term Atorvastatin Treatment,80mg/Day on Early Regression of Carotid Artery Atherosclerotic Lesions (External Link)
Candidates for bilateral carotid endarterectomy (CEA) who meet study criteria will provide informed consent before their randomization. Before the first CEA, the patient will have MRI, US, and EBCT exams …
Baylor Role:
Lead Sponsor
Completed
Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression of Peripheral Arterial Disease (The ELIMIT Study) (External Link)
PAD occurring in the legs is a serious disease that affects about 8 million people in the United States. A person's risk for PAD increases with age but can also …
Baylor Role:
Lead Sponsor
Completed
Diet, Exercise, Niacin, and Fenofibrate to Reduce Heart Disease Risk Factors in Individuals With HIV Lipodystrophy or Dyslipidemia (External Link)
BACKGROUND: HIV lipodystrophy syndrome is associated with both metabolic (e.g., dyslipidemia and insulin resistance) and anthropomorphic (e.g., lipoatrophy and central obesity) abnormalities. These defects are likely to predispose HIV patients …
Baylor Role:
Lead Sponsor