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64 Results

Recruiting
Micro-hematology Analyzer for Viral/Bacterial Description (External Link)
The purpose of the study is to evaluate the reliability and accuracy of a newly developed point-of-care analyzer, the CytoTracker, to measure complete blood count (CBC) parameters. The CytoTracker results …
Baylor Role: Collaborator
Recruiting
TETRAVI Multivirus CTL for Treatment of EBV, CMV, Adenovirus, and BK Infections Post Allogeneic SCT. (External Link)
The virus-specific T cells (VSTs) given to the patient will be thawed and injected into their intravenous line. To prevent an allergic reaction if the patient had a prior reaction …
Baylor Role: Lead Sponsor
Recruiting
Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients (External Link)
The objectives of this study are to dissect the main microbial, clinical, and antimicrobial resistance determinants that impact colonization and infection by vancomycin-resistant enterococci (VRE), extended-spectrum beta-lactamase producing Enterobacterales (ESBL-E), …
Baylor Role: Collaborator
Recruiting
Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis (External Link)
Approximately 5,000 children die from septic shock each year in the United States (US); thousands more die worldwide. Most children admitted with sepsis receive initial resuscitation in an emergency department …
Baylor Role: Collaborator
Active, Not Recruiting
Adolescent Sexually Transmitted Infection Screening in the Emergency Department (External Link)
Adolescents are disproportionately affected by sexually transmitted infections (STIs). The STI epidemic among youth is a national public health priority as noted in the Healthy People 2020 objectives, which specifically …
Baylor Role: Collaborator
Completed
Comparison of Men's Prevention Apps to Research Efficacy (External Link)
COMPARE is part of the iTech NIH U19, which has an overall goal to develop innovative technology-focused interventions addressing the HIV prevention and care continuum for youth. In years 1-2 …
Baylor Role: Collaborator
Completed
P3 (Prepared, Protected, emPowered) (External Link)
Sustainable, integrated PrEP adherence interventions are critically needed to reduce HIV incidence among YMSM and YTW. It is imperative that the investigators develop adherence interventions for YMSM and YTW initiating …
Baylor Role: Collaborator
Active, Not Recruiting
Efficacy of Na-GST-1/Alhydrogel Hookworm Vaccine Assessed by Controlled Challenge Infection (External Link)
Double blind, randomized, controlled, Phase 2 clinical trial in hookworm-unexposed adults living in the metropolitan area of Washington, DC. Subjects will receive three doses of the assigned vaccine formulation, or …
Baylor Role: Lead Sponsor
Withdrawn
Most Closely Human Leukocyte Antigen (HLA)-Matched Adenovirus-specific T Lymphocytes (Viralym-A) (External Link)
To make AdV-specific T cells (Viralym-A cells), small pieces of protein called peptides that come from AdV were mixed with blood cells from healthy donors. These peptides train a kind …
Recruiting
Assessment of Heparin Binding Protein for the Prediction of Severe Sepsis (External Link)
The primary objective of this study is to use HBP concentration to indicate the presence, or outcome, of severe sepsis (including septic shock) at admission and to predict the outcome …
Baylor Role: Collaborator