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Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis (External Link)
Approximately 5,000 children die from septic shock each year in the United States (US); thousands more die worldwide. Most children admitted with sepsis receive initial resuscitation in an emergency department …
Baylor Role:
Collaborator
Recruiting
Assessment of Heparin Binding Protein for the Prediction of Severe Sepsis (External Link)
The primary objective of this study is to use HBP concentration to indicate the presence, or outcome, of severe sepsis (including septic shock) at admission and to predict the outcome …
Baylor Role:
Collaborator
Withdrawn
Factors Associated With Increased Risk of Bacteremia and Cholangitis in ERCP With Cholangioscopy (External Link)
ERCP with cholangioscopy is becoming a widespread technique to treat complicated choledocholithiasis, document CBD clearance after stone extraction and to assess biliary duct strictures. During the procedure, a large amount …
Baylor Role:
Lead Sponsor
Completed
Home Away From Home - Medical Outcomes (External Link)
This is a bidirectional observational cohort study. Participants will be patients less that 19 years of age at diagnosis receiving or having received chemotherapy for AML from seventeen participating pediatric …
Baylor Role:
Collaborator
Completed
Rapid Test to Detect Staphylococcus Aureus in Blood and Wound Infections (External Link)
Staphylococcus aureus (SA) remains a major pathogen for human beings, causing infections of skin, soft tissue, bone, and other organs. Bacteremia due to this organism is common, and often occurs …
Baylor Role:
Collaborator
Unknown Status
A Novel Catheter Lock Solution for Treatment of Tunneled Hemodialysis Catheter-Associated Bacteremia (External Link)
The primary objective is to investigate the ability of systemic intravenous antibiotic plus antibiotic/anti-biofilm (i.e. N-acetylcysteine) lock catheter technique in eradicating uncomplicated catheter associated bacteremia and salvaging the infected vascular …
Baylor Role:
Lead Sponsor
Completed
Chart Review of Outcome of Treatment for S. Aureus Bacteremia (External Link)
Treatment of bacteremic infection (infection associated with positive blood cultures) due to Staphylococcus aureus has become increasingly problematic as a result of the increasing prevalence of strains that are resistant …
Baylor Role:
Collaborator
Completed
Study of the Relationship Between Feeding and Late Onset Sepsis and/or Necrotizing Enterocolitis in Low Birth Weight Infants (External Link)
PROTOCOL OUTLINE: This is a randomized, double blind study in arms I and II. Patients are randomized to receive either fortified pasteurized donor human milk (arm I) or preterm formula …
Baylor Role:
Collaborator