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Completed
Ceftaroline for Treatment of Hematogenously Acquired Staphylococcus Aureus Osteomyelitis in Children
This is a Phase 1/2, open-label, single-center study to determine safety and tolerability of Ceftaroline in pediatric subjects 1 to 17 years of age (inclusive) with signs and symptoms of …
Baylor Role: Lead Sponsor
Completed
Rapid Test to Detect Staphylococcus Aureus in Blood and Wound Infections
Staphylococcus aureus (SA) remains a major pathogen for human beings, causing infections of skin, soft tissue, bone, and other organs. Bacteremia due to this organism is common, and often occurs …
Baylor Role: Collaborator
Completed
Vancomycin vs. Nitazoxanide to Treat Recurrent C. Difficile Colitis
Clostridium difficile is the leading cause of nosocomial diarrheal disease associated with antibiotic therapy. This is a debilitating condition with substantial morbidity and a mortality that used to be said …
Baylor Role: Collaborator
Completed
Vancomycin vs. Vancomycin Plus Gentamycin in Treatment of MRSA Infection
Treatment of bacteremic infection (infection associated with positive blood cultures) due to Staphylococcus aureus has become increasingly problematic as a result of the increasing prevalence of strains that are resistant …
Baylor Role: Collaborator
Completed
Fecal Bacterial Flora in Clostridium Difficile-Associated Diarrhea
Clostridium difficile associated colitis is an increasing problem in hospitals throughout the developed world; the number of cases has increased, and the failure to respond to conventional therapy has become …
Baylor Role: Collaborator
Completed
Response of Clostridium Difficile Infection to Metronidazole Therapy
Clostridium difficile is a major cause of nosocomial infection. When this organism proliferates in the colon, usually as a result of prior antibiotic therapy in a hospitalized or otherwise debilitated …
Baylor Role: Collaborator
Completed
Association Between Response to Treatment of C. Diff Colitis and Anti-C.Diff Toxin Antibody
Clostridium difficile is the leading cause of nosocomial diarrheal disease associated with antibiotic therapy. This is a debilitating condition with substantial morbidity and mortality that may be around 2-3%. Current …
Baylor Role: Collaborator
Completed
Compassionate Use of Nitazoxanide for the Treatment of Clostridium Difficile Infection
Clostridium difficile is the leading cause of nosocomial diarrheal disease associated with antibiotic therapy. This is a debilitating condition with substantial morbidity and a mortality that may be around 2-3%. …
Baylor Role: Collaborator
Completed
CDC Anthrax Vaccine Clinical Trial
This study is a 43-month prospective, randomized, double-blind, placebo-controlled comparison of immunogenicity and reactogenicity elicited by BioThrax given by different routes of administration (SQ versus IM) and dosing regimens (as …
Baylor Role: Collaborator