Featured

Status

Health Topics

Any Category
Diseases
Bacterial Infections and Mycoses
Bacterial Infections
Clear Filters

Search Clinical Trials

15 Results
Recruiting
Closing -TB GAPs - for People Living With HIV: TB Guidance for Adaptable Patient-Centered Service
Tuberculosis (TB) is the world's leading infectious cause of mortality and responsible for 1/3 of deaths in people living with human immunodeficiency virus (PLHIV). Children and adolescents living with HIV …
Baylor Role: Lead Sponsor
Withdrawn
Azacytidine During Anti-tuberculosis Therapy
All study participants will have drug-sensitive TB and successfully complete 2 months of standard intensive phase 4-drug RHZE (rifampin, isoniazid, pyrazinamide, ethambutol). By definition, to have uncomplicated TB, participants will …
Recruiting
Evaluating a New Stool Based qPCR for Diagnosis of Tuberculosis in Children and People Living With HIV
Tuberculosis (TB) continues to be a leading cause of morbidity and mortality among children and people living with HIV (PLHIV). Despite significant progress in TB diagnostics, improvement of childhood TB …
Baylor Role: Collaborator
Completed
Ceftaroline for Treatment of Hematogenously Acquired Staphylococcus Aureus Osteomyelitis in Children
This is a Phase 1/2, open-label, single-center study to determine safety and tolerability of Ceftaroline in pediatric subjects 1 to 17 years of age (inclusive) with signs and symptoms of …
Baylor Role: Lead Sponsor
Terminated
Use Of Oral Fidaxomicin Vs. Oral Vancomycin For Clostridium Difficile Infection In Patients With Spinal Cord Injury
In recent clinical trials, comparing oral Vancomycin versus oral Fidaxomicin to treat Clostridium difficile, oral Fidaxomicin was shown to be the same in effectiveness as oral Vancomycin, but showed a …
Baylor Role: Lead Sponsor
Terminated
Early Methicillin-resistant Staphylococcus Aureus (MRSA) Therapy in Cystic Fibrosis (CF)
The STAR-too study is a randomized, open label, multi-center study in CF patients with new MRSA isolated from the respiratory tract (sputum or oropharyngeal (OP) swab). The purpose of the …
Baylor Role: Collaborator
Withdrawn
Addition of Lactobacillus to Metronidazole in Treatment of CDAD
Clostridium difficile associated disease (CDAD), which nearly always follows antibiotic therapy, has become increasingly common and important in American hospitals, causing substantial morbidity and mortality. Metronidazole is the recommended treatment …
Baylor Role: Collaborator
Completed
Rapid Test to Detect Staphylococcus Aureus in Blood and Wound Infections
Staphylococcus aureus (SA) remains a major pathogen for human beings, causing infections of skin, soft tissue, bone, and other organs. Bacteremia due to this organism is common, and often occurs …
Baylor Role: Collaborator
Completed
Vancomycin vs. Nitazoxanide to Treat Recurrent C. Difficile Colitis
Clostridium difficile is the leading cause of nosocomial diarrheal disease associated with antibiotic therapy. This is a debilitating condition with substantial morbidity and a mortality that used to be said …
Baylor Role: Collaborator
Completed
Vancomycin vs. Vancomycin Plus Gentamycin in Treatment of MRSA Infection
Treatment of bacteremic infection (infection associated with positive blood cultures) due to Staphylococcus aureus has become increasingly problematic as a result of the increasing prevalence of strains that are resistant …
Baylor Role: Collaborator