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Nitric Oxide During CPB to Reduce AKI in Neonates (External Link)
Screening: All patients undergoing either elective or emergency cardiac surgery will be screened against the eligibility criteria. Research Sample Collection: Blood and urine will be collected for the first 48 …
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Post Discharge Circadian Rhythms Post Adenotonsillectomy (External Link)
Wearable technology has tremendous advantages over current methods of assessing RTB activity in the post-discharge pediatric population after AT, which rely on quality of life (QOL) scales, caregiver and patient …
Baylor Role:
Lead Sponsor
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Ticagrelor vs. Prasugrel Effects on Infarct Size (External Link)
Subjects and research staff (including the Magnetic Resonance Imaging (MRI) readers and interventional cardiologists) will not know what active treatment study drug the subjects are receiving. Study Arm 1: Ticagrelor …
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The Effect of Ticagrelor on 15-Epi-Lipoxin A4 and Inflammation (External Link)
Clopidogrel, ticagrelor and prasugrel are routinely used for platelet inhibition in addition to aspirin in patients after acute coronary syndromes. The platelet inhibition and patient outcomes (PLATO) trial showed that …
Baylor Role:
Lead Sponsor
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Labetalol Versus Magnesium Sulfate (MgSO4) for the Prevention of Eclampsia Trial (External Link)
Research Design and Methods: The study will be a multicenter, randomized, controlled, clinical trial comparing the anti-seizure effect of parenteral and/or oral labetalol (n = 4000) versus parenteral (intravenous or …
Baylor Role:
Lead Sponsor
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Stem Cells for the Improvement of Erectile and Cardiac Function in Aging Men (External Link)
Baseline assessment of patients will include completion of 6 questionnaires, EKG (electrocardiogram), vision testing using a standard eye chart, markers of endothelial dysfunction hormone evaluation, laboratory blood tests, vital signs, …
Baylor Role:
Lead Sponsor
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Adjunctive Everolimus (RAD 001) Therapy for Epilepsy in Children With Sturge-Weber Syndrome (SWS) (External Link)
The main study part has 3 phases. The first phase is called the baseline phase and consists of 1-2 study site visit(s). During this phase, the investigators will gather information …
Baylor Role:
Lead Sponsor
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Umbilical Cord Blood in the Treatment of Stroke in Children. (External Link)
This study will enroll ten pediatric patients who have their umbilical cord blood banked with Cord Blood Registry, Inc. (CBR), who have been diagnosed with an arterial ischemic stroke (AIS), …
Baylor Role:
Collaborator
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Efficacy of Gabapentin in Prevention of Tourniquet Pain and Hypertension (External Link)
The purpose of the study is to find out if taking a dose of gabapentin 600 mg by mouth (po) before surgery will help prevent the development of tourniquet pain …
Baylor Role:
Lead Sponsor
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Developing a Diabetic Foot Ulcer Protocol (External Link)
This pilot study will be conducted in Harris County Hospital District (HCHD) Community Health Centers and Wound Care Clinics. The study will use random assignment of patients who meet inclusion …
Baylor Role:
Collaborator