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A Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain Management (External Link)
The management of pelvic floor overactivity (PFOA) using focal BoNT injection has been gaining clinical interest. Evidence has shown that BoNT injections to the levator ani in patients with CPP …
Baylor Role:
Collaborator
Not Yet Recruiting
Outpatient Pediatric Pulse Oximeters in Africa (External Link)
Background: Lower respiratory tract infections (LRI) remain the leading infectious cause of death globally for children younger than five years.1 Alarmingly, >50% of LRI deaths occurred in low and middle-income …
Baylor Role:
Collaborator
Not Yet Recruiting
Metformin IN Asthma for Overweight and Obese Individuals (MINA) (External Link)
This is a randomized, placebo-controlled, parallel-arm pilot clinical trial. Adult participants who are overweight or obese and have not well-controlled asthma despite use of an inhaled corticosteroid will be randomized …
Baylor Role:
Collaborator
Not Yet Recruiting
GpCRC Pediatric Gastroparesis Registry 2 (External Link)
An observational study to investigate the natural history and clinical course of children, adolescents, and young adults with symptoms of gastroparesis (e.g., nausea, vomiting, abdominal pain, bloating, distention) with either …
Baylor Role:
Collaborator
Not Yet Recruiting
Microbiome Alterations With Xylitol (MAX) in Pregnancy (External Link)
After consenting to the study, pregnant participants who have a singleton gestation and are <20 weeks' gestation will be randomised into either the intervention arm ( 6.36grams of daily xylitol; …
Baylor Role:
Lead Sponsor
Not Yet Recruiting
Heart Coherence Training on Vascular Ehlers-Danlos Syndrome Patients (External Link)
Vascular Ehlers Danlos Syndrome (VEDS) is caused by pathogenic variants of the COL3A1 gene, resulting abnormal Type III collagen protein. This impacts the body's connective tissue and makes people with …
Baylor Role:
Lead Sponsor
Not Yet Recruiting
A Pilot Study of Local Anesthesia for Inguinal Hernia Surgery in Older Adults (External Link)
The study rationale is that prior to conducting a multisite randomized trial, it is necessary to identify relevant outcomes, understand barriers to greater use of local anesthesia, test study procedures, …
Baylor Role:
Collaborator
Not Yet Recruiting
Novel Stimulation Patterns to Improve the Effectiveness of Spinal Cord Stimulation (External Link)
The researchers will conduct a traditional exploratory feasibility study using an investigational device to compare the clinical outcomes using time varying pulse (TVP) waveforms against time-invariant pulse (TIP) waveforms using …
Not Yet Recruiting
Efficacy of ActiveMatrix on Spinal SSI Rate (External Link)
Postoperative spinal surgical site infections (SSI) have a significant effect on patient morbidity and mortality.1 Spinal SSI as well as other complications including pseudoarthrosis occur at a higher rate in …
Baylor Role:
Lead Sponsor