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Completed
Mesenchymal Stromal Cells for the Treatment of SARS-CoV-2 Induced Acute Respiratory Failure (COVID-19 Disease) (External Link)
Earlier, a healthy donor provided blood cells to generate MSCs. These cells were grown and frozen for later use. Before being treated, the patient will receive a series of standard …
Baylor Role:
Lead Sponsor
Completed
Assessment of a PERT-free Nutritional Therapeutic Delivery System for Cystic Fibrosis (External Link)
This is a single center, randomized, double-blind, cross-over trial (with a follow-on single-blind safety evaluation stage), assessing a ready-to-drink nutritional supplement used without PERT ("PERT-free"), nutritional supplement for blood lipid …
Baylor Role:
Collaborator
Completed
Detecting Errors In Using Metered Dose Inhalers (MDI) Among Asthma And Chronic Obstructive Pulmonary Disease (COPD) Patients (External Link)
Metered Dose Inhaler (MDI) and Dry Powdered Inhaler (DPI) are the two most common platforms to deliver medicine for patients suffering from Asthma and chronic obstructive pulmonary disease, and are …
Baylor Role:
Lead Sponsor
Completed
CareSTEPS: A Supportive Care Program for the Caregivers of Advanced Lung Cancer Patients (External Link)
The profound symptom burden associated with advanced lung cancer (LC) makes caregiving a complex and burdensome task. Despite the input of outpatient palliative care services, LC families are often unprepared …
Baylor Role:
Lead Sponsor
Completed
Seattle-PAP Bubble Nasal CPAP and Work of Breathing (External Link)
The primary outcome variable is work of breathing (WOB) over a two hour period, estimated from pressure-rate products, which are assessed with 6 Fr (2 mm) catheters placed in the …
Baylor Role:
Collaborator
Completed
MethaCholine Bronchoprovocation Study (MeCIS) (External Link)
The study consists of two phases. The first phase is a cross-sectional, case-control study measuring the sensitivity and specificity of methacholine challenge testing for differentiating asthmatic participants from non-asthmatic controls. …
Baylor Role:
Collaborator
Completed
Oral Nadolol for the Treatment of Adults With Mild Asthma (External Link)
The purpose of this study is to confirm previous observations in asthmatics that chronic nadolol treatment reduces asthmatic airway hyper-responsiveness.
Baylor Role:
Collaborator
Completed
Effect of Curcumin on Lung Inflammation (External Link)
Chronic obstructive pulmonary disease (COPD) and lung cancer are leading causes of death and health care use. Diffuse airways inflammation is seen in COPD and is thought to be the …
Baylor Role:
Lead Sponsor
Completed
A Culturally Sensitive Values-Guided Aid for End of Life Decision-Making (External Link)
Background: End-of-life decision-making is an important aspect of providing quality healthcare, especially for the elderly population. Increasingly, the appropriateness of many of these decisions is being questioned. Some invasive procedures …
Baylor Role:
Collaborator
Completed
Pulmonary Infections Masquerading as Community-Acquired Pneumonia (External Link)
Guidelines to treat community acquired pneumonia (CAP) have been developed and widely promulgated by important professional societies in the past 10 years. The impetus to do so came from the …
Baylor Role:
Collaborator