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Completed
Prostate Cancer Symptom Management for Low Literacy Men (External Link)
Prostate cancer has recently surpassed lung cancer to become the most common cancer of American men. The estimated number of new prostate cancer cases in 2005 is expected to be …
Baylor Role:
Lead Sponsor
Completed
MTD Study of Vaccine BP-GMAX-CD1 Plus AP1903 to Treat Castrate Resistant Prostate Cancer (External Link)
Patients will be screened within 6 weeks prior to Week 1. A total of 3 cohorts, consisting of 3 to 6 patients each, are planned to receive five to eight …
Baylor Role:
Collaborator
Completed
Health-Related Quality of Life in Gay Men With Localized Prostate Cancer (External Link)
OBJECTIVES: - To enroll 200 gay men with localized prostate cancer in a cross-sectional study of prostate cancer outcomes. - To complete an R01 application using pilot data collected from …
Baylor Role:
Lead Sponsor
Completed
Evaluating Symptom Management Educational Materials for Patients With Prostate Cancer (External Link)
OBJECTIVES: - To collect formative evaluation data about a new educational intervention using focus groups of patients with prostate cancer. - To use the focus group data in the master's …
Baylor Role:
Lead Sponsor
Completed
Psychosocial and Patient Education Needs of Prostate Cancer Patients Selecting Watchful Waiting (External Link)
Interviews are conducted over the telephone and require approximately 90 minutes to complete. Men interviewed are compensated for their participation in the study.
Baylor Role:
Lead Sponsor
Completed
Phase I - Pre-Radical Prostatectomy RTVP-1 Gene Therapy for Prostate Cancer (External Link)
The population selected for this study includes patients with locally advanced and/or poorly differentiated tumors. These patients have an unacceptably high failure rate when treated by radical prostatectomy alone (over …
Baylor Role:
Lead Sponsor
Completed
Vaccine Therapy in Treating Patients With Metastatic, Progressive Prostate Cancer (External Link)
OBJECTIVES: Primary - Evaluate the safety and tolerance of NY-ESO-1/LAGE-1 class-I and class-II vaccine administered subcutaneously in patients with androgen-independent metastatic prostate cancer. Secondary - Compare the response induced by …
Baylor Role:
Lead Sponsor
Completed
PS-341 Followed by Removal of Prostate for Those With Prostate Cancer (External Link)
In murine and human xenograft tumor models, administration of PS-341 weekly was associated with significant antitumor activity. In primate studies using a schedule of twice weekly for six weeks, the …
Baylor Role:
Lead Sponsor
Completed
Vector Delivery of the IL-12 Gene in Men With Prostate Cancer (External Link)
The development of a clinical trial for gene therapy in prostate cancer will be coordinated with our collaborators at Baylor involved in similar studies in order to facilitate the approval …
Baylor Role:
Lead Sponsor