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Completed
Development & Testing of a Decision Aid for LVAD Placement (External Link)
The goal of this project is to develop a patient-centered decision aid for decision-making about end-stage heart failure treatment. This study seeks to create a decision aid that presents outcomes, …
Baylor Role:
Lead Sponsor
Completed
Patients With Intermittent Claudication Injected With ALDH Bright Cells (External Link)
Peripheral Artery Disease (PAD) occurs when arteries in the arms and legs (most often the legs) become narrowed by plaque. Because of this plaque, patients with PAD are also at …
Completed
Study of Dopamine Versus Vasopressin for Treatment of Low Blood Pressure in Low Birth Weight Infants (External Link)
Hypotension in the low birth weight (LBW) and extremely low birth weight (ELBW) infant is often encountered in the postnatal adaptation phase. Severe, prolonged hypotension contributes to cellular dysfunction and …
Baylor Role:
Lead Sponsor
Completed
Nitric Oxide Production in MELAS Syndrome (External Link)
What does the study involve? Individuals with MELAS syndrome will be admitted twice to the General Clinical Research Center (GCRC) at Texas Children's Hospital. Each time they will stay for …
Baylor Role:
Lead Sponsor
Completed
Improving Outcomes Using Collaborative Group Clinics to Empower Older Patients (External Link)
Among persons aged 55-84 years, over 65% have one to three common medical conditions (e.g., hypertension, diabetes, arthritis, stroke, heart disease, etc.). Fortunately, large randomized clinical trials have demonstrated the …
Baylor Role:
Lead Sponsor
Completed
Time to Defibrillation Using Automated External Defibrillators by Pediatric Residents in Simulated Cardiac Arrests (External Link)
Automated external defibrillators have improved survival for adult in hospital cardiac arrest. Automated external defibrillators are approved for children aged 1 year and older for out of hospital cardiac arrests. …
Baylor Role:
Lead Sponsor
Completed
Erythropoetin Neuroprotection for Neonatal Cardiac Surgery (External Link)
Hypothesis: Erythropoetin (EPO) will protect the neonatal brain in the perioperative period for congenital heart surgery. Using a prospective, randomized, placebo-controlled, double-blinded design, the specific aims of this study are: …
Baylor Role:
Lead Sponsor
Completed
Collaborative Care for Heart Failure Patients With the Metabolic Syndrome (External Link)
A striking feature of the Harris County Hospital District heart failure population is that the prevalence of obesity (50.8%) and the metabolic syndrome (48.9%) exceeds that of the general U.S. …
Baylor Role:
Lead Sponsor
Completed
The Effect of Diet and Exercise in Heart Failure (External Link)
A growing number of people in this country are overweight or obese. This is concerning as increasing weight has been shown to increase the risk of developing heart failure. However, …
Baylor Role:
Lead Sponsor
Completed
A Culturally Sensitive Values-Guided Aid for End of Life Decision-Making (External Link)
Background: End-of-life decision-making is an important aspect of providing quality healthcare, especially for the elderly population. Increasingly, the appropriateness of many of these decisions is being questioned. Some invasive procedures …
Baylor Role:
Collaborator