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Completed
Long-term Lifestyle Change and Testosterone Replacement (External Link)
Background: There are studies on long-term testosterone replacement in older adults with hypogonadism showing benefits on body composition, sexual function and mood but not on testosterone replacement therapy in combination …
Baylor Role:
Lead Sponsor
Completed
Lifestyle Intervention and Testosterone Replacement in Obese Seniors (External Link)
Obesity is not only highly prevalent among Americans, but even more so among Veterans using VA medical facilities. Failure to assist Veterans in managing weight and sedentary lifestyle affects current …
Baylor Role:
Collaborator
Completed
Biomarker Guided Therapies in Stage A/B Heart Failure (External Link)
Recently the investigators have shown that HF risk prediction can be improved using cardiac troponin T measured with a novel high-sensitivity assay (hs-cTnT) and N-terminal pro-B-type natriuretic peptide (NT-proBNP). Furthermore, …
Baylor Role:
Collaborator
Completed
Effects of Dry Eye Treatments on the Ocular Surface (External Link)
This study evaluated the effects of the corticosteroid dexamethasone on suppressing development of eye irritation, cornea epithelial disease and increased production of inflammatory mediators in subjects who were subjected to …
Baylor Role:
Lead Sponsor
Completed
Dose Adjusted EPOCH-R, to Treat Mature B Cell Malignancies (External Link)
The subject will need to have a variety of tests, exams, or procedures to find out if s/he can be on the study. The subject will also require placement of …
Baylor Role:
Lead Sponsor
Completed
Chemotherapy With or Without Radiation, Low and Intermediate Risk Hodgkins Lymphoma, TXCH-HD-12A (External Link)
At first the subject will have 2 cycles of cancer drugs (Doxorubicin, Bleomycin, Vincristine, Etoposide, Prednisone, Cyclophosphamide). The doctors call this combination of cancer drugs ABVE-PC for short. A cycle …
Baylor Role:
Lead Sponsor
Completed
The Management of Glucocorticoid-Induced Hyperglycemia in Hospitalized Patients (External Link)
The target fasting serum glucose (FSG) and pre-meal SG was 90-140 mg/dL, and the random SG was less than 180 mg/dL, taking into consideration the ADA/AACE target glucose levels in …
Baylor Role:
Lead Sponsor
Completed
Carboplatin and Docetaxel Followed by Epstein-Barr Virus Cytotoxic T Lymphocytes (External Link)
A blood sample will be obtained to start making the CTLs before the patient begins chemotherapy. The patients EBV-specific T cells will be grown while the patient is being treated …
Baylor Role:
Lead Sponsor
Completed
Evaluation of Calcium, Vitamin D, Magnesium, and Zinc Absorption in Children (External Link)
We plan to stratify subjects for randomization to either vitamin D supplements or placebo by serum 25-hydroxyvitamin D (25 OHD) into three groups: 0-20 ng/mL, 20-32 ng/mL, and >32 ng/mL. …
Baylor Role:
Lead Sponsor
Completed
MethaCholine Bronchoprovocation Study (MeCIS) (External Link)
The study consists of two phases. The first phase is a cross-sectional, case-control study measuring the sensitivity and specificity of methacholine challenge testing for differentiating asthmatic participants from non-asthmatic controls. …
Baylor Role:
Collaborator