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10 Results
Completed
Intranasal Dexmedetomidine Sedation in Children for Non-painful Procedures
Dexmedetomidine (DEX) is an alpha-2 receptor agonist with sedative, anxiolytic, and analgesics properties. DEX has been used extensively for sedation in children to facilitate different non-painful procedures, such magnetic resonance …
Baylor Role: Collaborator
Completed
A Pilot Study to Assess the Glucose Lowering Effect of Metformin and Sitagliptin in Adolescents With Type 1 Diabetes
- The study will include a total of 4 visits. The time period between the very first visit and the very last visit will be between 10 and 15 weeks. …
Baylor Role: Lead Sponsor
Completed
A Trial Of Oral Chloral Hydrate Versus Intranasal Dexmedetomidine For Sedated Abr Exams
The purpose of this study is to compare the efficacy of oral chloral hydrate to intranasal dexmedetomidine for the successful completion of a sedated ABR exam (hearing exam).
Baylor Role: Lead Sponsor
Completed
Investigation of Cycloserine as a Smoking Cessation Treatment
See brief summary
Baylor Role: Lead Sponsor
Completed
Sequential and Hybrid Therapies for H Pylori Infection
The purpose of this study is to test whether the 14-day sequential therapy ( esomeprazole plus amoxicillin dual therapy for 7 days followed by triple therapy with esomeprazole, clarithromycin, and …
Baylor Role: Collaborator
Completed
Comparison of Sequential or Concomitant Therapy for Helicobacter Pylori Infection
The purpose of this study is to compare different methods of giving combination drug therapy for treating Helicobacter pylori infection of the stomach. The entire study will last less than …
Baylor Role: Collaborator
Completed
Research Study for Major Depressive Disorder: Investigation of Glutamate Medications
This research proposal will investigate a glutamate-modulating agent, riluzole, in treatment-resistant patients who exhibit an acute, sustained response to a single dose of intravenous (IV) racemic ketamine. Fifty ketamine-responders will …
Baylor Role: Lead Sponsor
Completed
Dietary Supplements for the Treatment of Angelman Syndrome
AS is a neurologic disorder that may cause developmental delay, mental retardation, severe speech impairment, seizures, small head size, and problems with movement and balance in young children. AS is …
Baylor Role: Collaborator
Completed
Dexmedetomidine in Pediatric Tonsillectomy
Dexmedetomidine, an alpha 2 agonist provides some analgesia without respiratory depression. Children undergoing tonsillectomy and adenoidectomy occasionally have episodes of respiratory obstruction in the recovery room following administration of opioids. …
Baylor Role: Lead Sponsor
Completed
Response of Clostridium Difficile Infection to Metronidazole Therapy
Clostridium difficile is a major cause of nosocomial infection. When this organism proliferates in the colon, usually as a result of prior antibiotic therapy in a hospitalized or otherwise debilitated …
Baylor Role: Collaborator