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Active, Not Recruiting
A Practical Platform for In-Home Remote Monitoring of Cognitive Frailty
The investigators are proposing to evaluate the feasibility and accuracy of the Frailty Meter (FM), a cutting-edge video-based solution for remotely assessing frailty. FM determines frailty phenotypes, such as weakness, …
Baylor Role: Lead Sponsor
Active, Not Recruiting
An Innovative Platform for Objective Monitoring of Instrumental Activities of Daily Living
This innovative platform, called IADLSys, will detect the timing and type of IADL for a wide range of daily functions, and will also monitor the user's physical activity and life-space. …
Active, Not Recruiting
T Cells Expressing HER2-specific Chimeric Antigen Receptors(CAR) for Patients With HER2-Positive CNS Tumors
First, to find out if HER2 is expressed in the patient's brain cancer, the investigators will need to obtain the tissue block or tissue specimen that was used to make …
Baylor Role: Lead Sponsor
Active, Not Recruiting
The CSF Shunt Entry Site Trial
The study is a multi-centered, randomized, controlled trial comparing two commonly used CSF shunt insertion techniques, anterior and posterior entry site. There is conflicting information and opinions in the pediatric …
Baylor Role: Lead Sponsor
Active, Not Recruiting
BEnefits of Stroke Treatment Delivered Using a Mobile Stroke Unit
There are many ways that use of a MSU might prove valuable in stroke patients, but we will focus on acute ischemic stroke (AIS) and treatment with IV tissue plasminogen …
Baylor Role: Collaborator
Active, Not Recruiting
Multicenter Evaluation of Memory Remediation After TBI With Donepezil
BACKGROUND: Memory deficits are among the most common chronic and functionally important consequences of traumatic brain injury (TBI). Basic and clinical research studies suggest that persistent deficits in verbal memory …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Phenylbutyrate Therapy for Maple Syrup Urine Disease
Maple syrup urine disease is a severe inborn error of amino acid metabolism caused by deficiency of the mitochondrial branched-chain alpha-ketoacid dehydrogenase complex (BCKDC) resulting in the accumulation of branched-chain …
Active, Not Recruiting
Innovative Approaches to Gauge Progression of Sturge-Weber Syndrome
This study is one of three projects of an NIH Rare Disease Clinical Research Consortium focused on brain blood vessel malformations in three different rare diseases. The focus of this …
Baylor Role: Collaborator
Active, Not Recruiting
304-C03/L3301n: Effects of Growth Hormone on Glucose and Protein Metabolism in Children With Growth Hormone Deficiency
Children with growth hormone deficiency (GHD) have increased insulin sensitivity and may present with hypoglycemia during infancy. Treatment with recombinant human growth hormone (rhGH) reduces the risk for hypoglycemia and …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Photorefractive Keratectomy for Severe Anisometropia and Isoametropia Associated With Amblyopia
Anisometropia is a condition in which one eye has a significantly different refractive error from the other and commonly leads to the development of refractive amblyopia in the affected eye. …
Baylor Role: Lead Sponsor