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92 Results
Completed
Erythropoetin Neuroprotection for Neonatal Cardiac Surgery
Hypothesis: Erythropoetin (EPO) will protect the neonatal brain in the perioperative period for congenital heart surgery. Using a prospective, randomized, placebo-controlled, double-blinded design, the specific aims of this study are: …
Baylor Role: Lead Sponsor
Terminated
Treatment of Subarachnoid Hemorrhage With Human Albumin
The proposed study was set up to evaluate the tolerability and safety of 25% human albumin (HA) therapy in patients with subarachnoid hemorrhage (SAH). It is estimated that 37,500 people …
Baylor Role: Lead Sponsor
Completed
Collaborative Care for Heart Failure Patients With the Metabolic Syndrome
A striking feature of the Harris County Hospital District heart failure population is that the prevalence of obesity (50.8%) and the metabolic syndrome (48.9%) exceeds that of the general U.S. …
Baylor Role: Lead Sponsor
Unknown Status
Effect of Short Term Atorvastatin Treatment,80mg/Day on Early Regression of Carotid Artery Atherosclerotic Lesions
Candidates for bilateral carotid endarterectomy (CEA) who meet study criteria will provide informed consent before their randomization. Before the first CEA, the patient will have MRI, US, and EBCT exams …
Baylor Role: Lead Sponsor
Terminated
Treatment of Subarachnoid Hemorrhage With Human Albumin
An estimated 37,500 people in the United States have subarachnoid hemorrhage (SAH) every year. SAH is usually secondary to a brain aneurysm that has burst. In SAH the bleeding accumulates …
Baylor Role: Lead Sponsor
Withdrawn
Pharmacogenomics in Pulmonary Arterial Hypertension
This study will make use of a large population of well defined patients with Pulmonary Arterial Hypertension who were enrolled in Encysive Pharmaceutical's STRIDE clinical trials or who have received …
Baylor Role: Collaborator
Completed
The Effect of Diet and Exercise in Heart Failure
A growing number of people in this country are overweight or obese. This is concerning as increasing weight has been shown to increase the risk of developing heart failure. However, …
Baylor Role: Lead Sponsor
Completed
A Culturally Sensitive Values-Guided Aid for End of Life Decision-Making
Background: End-of-life decision-making is an important aspect of providing quality healthcare, especially for the elderly population. Increasingly, the appropriateness of many of these decisions is being questioned. Some invasive procedures …
Baylor Role: Collaborator
Completed
Physician Uncertainty Reduction for Hypertension
BACKGROUND: A large amount of literature suggests that the majority of "uncontrolled" hypertensives are under medical care, and that lack of control is largely explained by physicians not intensifying treatment …
Baylor Role: Lead Sponsor
Completed
Novel Treatment for Diastolic Heart Failure in Women
Subjects with diastolic heart failure defined based on clinical symptoms, echocardiography diastology parameters and brain natriuretic peptide level will be randomized in a 1:1 fashion to either placebo or spironolactone …
Baylor Role: Lead Sponsor