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Pilot RCT of an Obesity Intervention for Primary Care Pediatrics: Helping HAND (External Link)
This is a feasibility study to evaluate a 6-month obesity treatment intervention (Helping HAND: Health Activity and Nutrition Directions) for pediatric primary care clinics. The program targets 5-8 year old …
Baylor Role:
Lead Sponsor
Completed
Propofol in Obese Children (External Link)
All subjects were fasted in keeping with our institutional NPO guidelines and had IV access established in the upper extremity in the pre-anesthesia area. No pre-induction sedative drugs were administered. …
Baylor Role:
Lead Sponsor
Completed
Understanding Sleep Problems in Children With Autism Spectrum Disorder (External Link)
This is a proposal to study the relationship between melatonin (MT) and sleep problems in children with autism spectrum disorder (ASD), as part of the collaborative research structure of the …
Baylor Role:
Lead Sponsor
Completed
Does Potassium Bicarbonate Improve the Effect of Dietary Protein on Bone and Muscle? (External Link)
The balance between the amount of protein in the diet (anabolic component) and the net acid load of the diet (catabolic component) in part determines whether the diet as a …
Baylor Role:
Collaborator
Completed
Pregabalin in the Treatment of Essential Tremor (External Link)
Overview We propose a single site, double-blind, placebo-controlled, cross-over design. Drug will be administered in 75mg capsules with a target dose of 300 mg/day. Pregabalin will be titrated upward as …
Baylor Role:
Lead Sponsor
Completed
Fecal Bacterial Flora in Clostridium Difficile-Associated Diarrhea (External Link)
Clostridium difficile associated colitis is an increasing problem in hospitals throughout the developed world; the number of cases has increased, and the failure to respond to conventional therapy has become …
Baylor Role:
Collaborator
Completed
Family Lifestyle Overweight Prevention Program (External Link)
The overall objective of this study is to compare the effectiveness of a behavioral, family-based weight management program and a self-help only group for the prevention of obesity in adolescents. …
Baylor Role:
Lead Sponsor
Completed
Trial of Xyrem for Excessive Daytime Sleepiness and Sleep Disturbance in Parkinson's Disease (PD) (External Link)
Inclusion required an Epworth Sleepiness Scale (ESS) score greater than 10 and any subjective nocturnal sleep concern, usually insomnia. An acclimation and screening polysomnogram was performed to exclude subjects with …
Baylor Role:
Lead Sponsor
Completed
Corticosteroids in Postoperative Critically Ill Neonates With Low Cardiac Output Syndrome With Congenital Heart Disease (External Link)
The study will be prospective. Patients who meet entry criteria will be randomized to receive corticosteroids versus placebo. Randomization will take into account biventricular versus univentricular repairs/palliations and whether the …
Baylor Role:
Lead Sponsor
Completed
Preventing Overweight in USAF Personnel: Minimal Contact Program (External Link)
The objective of this study is to compare the relative effectiveness of two approaches to weight management, using a controlled comparison experiment. The two approaches are: Minimal Contact Behavior Therapy …
Baylor Role:
Lead Sponsor