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Search Clinical Trials
Completed
Efficacy of Na-GST-1/Alhydrogel Hookworm Vaccine Assessed by Controlled Challenge Infection (External Link)
Double blind, randomized, controlled, Phase 2 clinical trial in hookworm-unexposed adults living in the metropolitan area of Washington, DC. Subjects will receive three doses of the assigned vaccine formulation, or …
Baylor Role:
Lead Sponsor
Completed
The PediQUEST Response Intervention Study (External Link)
Background: Integration of palliative care (PC) has been associated with better health related quality of life (HRQoL) and longer survival in adults and their caregivers. Yet, only a few randomized …
Baylor Role:
Collaborator
Completed
Tranexamic Acid Per Inhalation for Treatment of Pulmonary Hemorrhage in Pediatric Patients (External Link)
Pulmonary hemorrhage can be severe and life-threatening. In children, etiologies of pulmonary hemorrhage include respiratory infection, foreign bodies, bronchiectasis, pulmonary vascular disorders, parenchymal lung disease, and post-surgical complications. Initial management …
Baylor Role:
Lead Sponsor
Completed
Na-GST-1/Alhydrogel With or Without CpG 10104 in Gabonese Adults (External Link)
Double blind, randomized, controlled, dose-escalation Phase 1 clinical trial in hookworm-exposed adults aged 18 to 50 years living in the area of Lambaréné, Gabon. Participants will receive three doses of …
Baylor Role:
Lead Sponsor
Completed
Technology to Improve the Health of Resource-poor Hispanics With Diabetes (External Link)
The number of Hispanics diagnosed with diabetes is escalating in the US with disproportionately higher prevalence and complication rates than other ethnicities. CHWs are a well-established and culturally sensitive means …
Baylor Role:
Lead Sponsor
Completed
Entolimod, an Adjuvant for Vaccine Augmentation (External Link)
This is a single-blind (participants are blinded), pilot study with no therapeutic or diagnostic intent and limited drug exposure. The study will be conducted at Baylor College of Medicine in …
Baylor Role:
Lead Sponsor
Completed
Chronic Liver Disease in Urea Cycle Disorders (External Link)
Urea cycle disorders (UCDs) are among the most common inborn errors of liver metabolism.With early diagnosis and improved treatments, the survival of individuals with UCDs has improved, and this improved …
Baylor Role:
Lead Sponsor
Completed
Safety of Fresolimumab in the Treatment of Osteogenesis Imperfecta (External Link)
Osteogenesis Imperfecta (OI) is a rare disorder that causes bones to break easily. People with OI may have broken bones with little or no trauma, dentinogenesis imperfecta (DI), and, in …
Baylor Role:
Lead Sponsor
Completed
Effect of Monochromatic Light on Incidence of Emergence Delirium in Children (External Link)
Emergence delirium/emergence agitation (ED/EA) is a behavioral phenomenon of unclear etiology consisting of short lived behavioral changes that can be both traumatic to families and pose a safety risk to …
Baylor Role:
Lead Sponsor
Completed
Get Connected Efficacy Trial (External Link)
The number of HIV infections among men who have sex with men aged 15-24 (YMSM) has grown significantly in the past decade. For YMSM to successfully engage in HIV prevention …
Baylor Role:
Collaborator