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Active, Not Recruiting
HPV-16/18 E6/E7-Specific T Lymphocytes, Relapsed HPV-Associated Cancers, HESTIA (External Link)
HPV is found in the cancer cells of more than half the patients with certain types of cancer, suggesting that it may play a role in causing the cancer. The …
Baylor Role:
Lead Sponsor
Completed
NextSteps Intervention for Advanced Cancer Patients and Caregivers (External Link)
In this study, 200 advanced cancer patients who are within one month of treatment initiation (baseline) and their caregivers will complete baseline surveys and be randomized to NextSTEPS or a …
Baylor Role:
Lead Sponsor
Completed
The Feasibility of Self or Partner-assisted Digital Anal Exam Screening (External Link)
There is no standard screening protocol for anal cancer even as disease incidence and mortality increases; however, a digital anorectal exam (also called a digital rectal exam) will play a …
Baylor Role:
Collaborator
Completed
Microbiome Fructan Metabolism and Symptoms in Childhood IBS (External Link)
Fructans (fructo-oligosaccharides) are a type of carbohydrate which can not be hydrolyzed by humans. It is commonly found in wheat in the American diet. After ingestion they arrive essentially intact …
Baylor Role:
Lead Sponsor
Completed
Fecal Microbiota Transplantation (FMT) for Treatment of Ulcerative Colitis in Children (External Link)
FMT RECIPIENTS: Participants will be recruited from the patient population treated by the Pediatric Gastroenterology, Hepatology, and Nutrition Section at Baylor College of Medicine/Texas Children's Hospital. I. Activities prior to …
Baylor Role:
Lead Sponsor
Completed
Non-invasive Biomarkers of Fibrosis in Pediatric Liver Diseases (External Link)
Abnormal liver biochemical and function tests are frequently detected in symptomatic patients since many screening blood test panels routinely include them. A population-based survey in the United States conducted between …
Baylor Role:
Lead Sponsor
Terminated
Eosinophilic Esophagitis Clinical Therapy Comparison Trial (External Link)
This study is a open label, randomized, prospective clinical trial comparing the efficacy of a topical steroid preparation to an antigen (food) elimination diet. A total of 40 participants will …
Baylor Role:
Lead Sponsor
Active, Not Recruiting
Morphological Markers of Gastroesophageal Reflux Disease (GERD) (External Link)
This will be a prospective case control study. Children between the ages of 8 and 18 with suspected gastroesophageal reflux disease (GERD) or eosinophilic esophagitis (EoE) based on symptom criteria …
Baylor Role:
Lead Sponsor
Enrolling By Invitation
Defined Fecal Microbiota Transplantation for Clostridium Difficile Diarrhea (External Link)
This study will initially enroll 12 subjects. Based on the relatively large experience with FMT reported to date, we anticipate a prompt and sustained response as determined by a cessation …
Baylor Role:
Lead Sponsor
Terminated
Pentoxifylline Therapy in Biliary Atresia (External Link)
Biliary atresia (BA) is a devastating liver disease of infancy of unknown etiology, characterized by bile duct obstruction, live fibrosis, and cirrhosis. BA has no known medical treatments. The only …
Baylor Role:
Lead Sponsor