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Neoadjuvant Chemoimmunotherapy for Resectable Non-Metastatic Proficient Mismatch Repair (PMMR) Colon Cancer (External Link)
Once participants' eligibility has been confirmed, and participants have been registered in the study, the participants will receive immunotherapy treatment with Atezolizumab, followed by administration of CAPEOX chemotherapy for a …
Baylor Role:
Lead Sponsor
Not Yet Recruiting
Effectiveness and Performance of an Optical Biopsy Technology for Esophageal Cancer in Brazil and the United States (External Link)
The investigators' hypothesis is that the artificial intelligence (AI) mobile, high-resolution microendoscope (mHRME) will increase the accuracy of Lugol's chromoendoscopy (LCE) in endoscopic cancer detection in low- and middle-income countries …
Baylor Role:
Lead Sponsor
Not Yet Recruiting
Novel Rigidizing Overtube in Colonic Endoscopic Submucosal Dissection (External Link)
Endoscopic submucosal dissection (ESD) is preferred resection method for advanced colonic polyp due to its higher rates of en bloc and R0 resection which lead to higher curative resection rate.1 …
Baylor Role:
Lead Sponsor
Not Yet Recruiting
Monopolar and Bipolar in Esophageal ESD (External Link)
Endoscopic submucosal dissection (ESD) is a novel technique for the removal of esophageal lesions or polyps with high-risk features. ESD is minimally invasive and allows the removal of esophageal polyps …
Baylor Role:
Lead Sponsor
Recruiting
National Liver Cancer Screening Trial (External Link)
The TRACER phase IV biomarker study is a randomized trial comparing ultrasound-based screening versus a biomarker-based strategy in patients with cirrhosis. In brief, 5500 patients with cirrhosis from any etiology …
Baylor Role:
Collaborator
Recruiting
Traction vs. No Traction in Colonic ESD (External Link)
Endoscopic submucosal dissection (ESD) is the mainstay for the treatment of complex colorectal polyps particularly those with a higher risk of superficial submucosal invasion. However, colonic ESD is technically difficult …
Baylor Role:
Lead Sponsor
Completed
Cost-effective Analysis of Two Approximation Devices in Closure of Gastrointestinal Defects (External Link)
Closure of GI defects after endoscopic resection decreases the rate of post resection bleeding. Traditionally, standard TTS clips have been used to close GI wall defects with some success. However, …
Baylor Role:
Lead Sponsor
Recruiting
Improving Comprehensive Care of Cancer Patients (External Link)
Design Overview. This is a randomized controlled trial of a consecutive sample of 300 medically underserved breast, GI, and hematological cancer patients with comorbidities recruited from Harris Health Ben Taub …
Baylor Role:
Lead Sponsor
Active, Not Recruiting
Monopolar Current Cutting Knife vs Bipolar RFA Knife (External Link)
Endoscopic submucosal dissection (ESD) is a novel technique for the removal of advanced colonic polyps with high-risk features. ESD is minimally invasive and allows the removal of colonic adenomatous polyp …
Baylor Role:
Lead Sponsor
Completed
Acceptability and Performance of a Mobile Optical Biopsy Technology for Gastrointestinal Cancer Screening (External Link)
The investigators' hypothesis is that this mobile device with automated, AR optical biopsy diagnoses can efficiently and accurately facilitate endoscopic cancer detection in low to middle income countries (LMICs) with …
Baylor Role:
Collaborator