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- Acid-Base Imbalance 1
- Bone Diseases, Metabolic 4
- Brain Diseases, Metabolic 7
- DNA Repair-Deficiency Disorders 1
- Glucose Metabolism Disorders 36
- Iron Metabolism Disorders 5
- Lipid Metabolism Disorders 3
- Malabsorption Syndromes 2
- Metabolic Syndrome 4
- Metabolism, Inborn Errors 9
- Mitochondrial Diseases 1
- Skin Diseases, Metabolic 2
- Wasting Syndrome 1
- Water-Electrolyte Imbalance 1
Search Clinical Trials
Completed
Ability to Cope With Type 1 Diabetes (External Link)
Coping with type 1 diabetes can be very difficult. Type 1 diabetes is a very unique chronic disease because it requires constant attention to several responsibilities such as daily glucose …
Baylor Role:
Lead Sponsor
Completed
Ability to Cope With Type 1 Diabetes (External Link)
Coping with type 1 diabetes can be very difficult. Type 1 diabetes is a very unique chronic disease because it requires constant attention to several responsibilities such as daily glucose …
Baylor Role:
Lead Sponsor
Completed
Diet, Exercise, Niacin, and Fenofibrate to Reduce Heart Disease Risk Factors in Individuals With HIV Lipodystrophy or Dyslipidemia (External Link)
BACKGROUND: HIV lipodystrophy syndrome is associated with both metabolic (e.g., dyslipidemia and insulin resistance) and anthropomorphic (e.g., lipoatrophy and central obesity) abnormalities. These defects are likely to predispose HIV patients …
Baylor Role:
Lead Sponsor
Completed
The Effect of Prolonged Pramlintide Infusion in Pediatric Diabetes (External Link)
The Diabetes Control and Complications Trial (DCCT) showed that improving blood sugar control for individuals with Type 1 diabetes (T1DM) stopped or delayed the onset of long-term complications. As a …
Baylor Role:
Lead Sponsor
Completed
Leptin for Abnormal Lipid Kinetics in HIV Lipodystrophy Syndrome (External Link)
The HIV lipodystrophy syndrome (HLS) is characterized by peripheral fat wasting and central obesity, and hyperlipidemia (mainly hypertriglyceridemia), which results in insulin resistance. HLS patients are at high risk for …
Baylor Role:
Lead Sponsor
Completed
The Role of Amylin and Glucagon in T1DM (External Link)
Objective: To develop a new treatment approach in the prevention of hypo and hyperglycemia in children with type 1diabetes. Background/Rationale: The diabetes control and complications trial (DCCT) showed that improving …
Baylor Role:
Lead Sponsor
Completed
Encouraging Calcium Absorption and Bone Formation During Early Puberty (External Link)
Rapid increases in bone mass occur during calcium absorption and bone calcium deposition during puberty, and these increases can enhance peak bone mass and ultimately decrease the lifetime risk of …
Baylor Role:
Lead Sponsor
Completed
Safety and Effectiveness of Soy Phytoestrogens to Prevent Bone Loss (External Link)
Over-the-counter soy isoflavone supplement usage is becoming common among postmenopausal women. However, there is no documented scientific evidence of its long-term safety and efficacy in preventing osteoporosis. Our primary goal …
Baylor Role:
Lead Sponsor
Completed
Phase II Study of the Effect of Leuprolide Acetate and Spironolactone on Insulin Resistance in Hyperandrogenic Women With Polycystic Ovarian Disease or Hyperandrogenism Insulin Resistance Acanthosis Nigricans Syndrome (External Link)
PROTOCOL OUTLINE: Participants are treated with subcutaneous leuprolide acetate followed by oral spironolactone. Each treatment is administered daily for 6 weeks, with a 6-week washout between drugs. Patients and controls …
Baylor Role:
Collaborator